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Institution Date Title Author
國家衛生研究院 2025-07-14 Contribution of prostaglandin E2-induced neuronal excitation to drug resistance in glioblastoma countered by a novel blood-brain barrier crossing celecoxib derivative Shen, CJ;Chen, HC;Lin, CL;Thakur, A;Onuku, R;Chen, IC;Li, HY;Chang, KY;Chuang, JY;Yang, WB;Lin, HY;Shen, YR;Liou, JP;Chang, WC;Hsu, TI
國家衛生研究院 2025-02 Development of BACE2-IN-1/tranylcypromine-based compounds to induce steroidogenesis-dependent neuroprotection Banerjee, S;Hsu, YT;Nguyen, DH;Yeh, SH;Liou, KC;Liu, JJ;Liou, JP;Chuang, JY
國家衛生研究院 2025-01-21 Repurposing linezolid in conjunction with histone deacetylase inhibitor access in the realm of glioblastoma therapies Chen, IC;Lin, HY;Liu, ZY;Cheng, WJ;Yeh, TY;Yang, WB;Tran, HY;Lai, MJ;Wang, CH;Kao, TY;Hung, CY;Huang, YL;Liou, KC;Hsieh, CM;Hsu, T;Liou, JP
國家衛生研究院 2024-04-01 Dual inhibition of CYP17A1 and HDAC6 by abiraterone-installed hydroxamic acid overcomes temozolomide resistance in glioblastoma through inducing DNA damage and oxidative stress Sharma, R;Chiang, YH;Chen, HC;Lin, HY;Yang, WB;Nepali, K;Lai, MJ;Chen, KY;Liou, JP;Hsu, TI
國家衛生研究院 2024-01-29 First-in-class dual EZH2-HSP90 inhibitor eliciting striking antiglioblastoma activity in vitro and in vivo Sharma, S;Wang, SA;Yang, WB;Lin, HY;Lai, MJ;Chen, HC;Kao, TY;Hsu, FL;Nepali, K;Hsu, TI;Liou, JP
國家衛生研究院 2023-08 Design, synthesis, and biological activity of dual monoamine oxidase A and heat shock protein 90 inhibitors, N-Methylpropargylamine-conjugated 4-isopropylresorcinol for glioblastoma Tseng, HJ;Banerjee, S;Qian, B;Lai, MJ;Wu, TY;Hsu, TI;Lin, TE;Hsu, KC;Chuang, KH;Liou, JP;Shih, JC
國家衛生研究院 2023-07-22 The complex role of eicosanoids in the brain: Implications for brain tumor development and therapeutic opportunities Chen, HC;Chang, WC;Chuang, JY;Chang, KY;Liou, JP;Hsu, TI
國家衛生研究院 2022-12-05 2,6-Difluorobenzamide derivatives as store-operated calcium channel (SOC) inhibitors Wang, YS;Yeh, TK;Chang, WC;Liou, JP;Liu, YM;Huang, WC
國家衛生研究院 2022-02-02 HDAC6 involves in regulating the lncRNA-microRNA-mRNA network to promote the proliferation of glioblastoma cells Wu, AC;Yang, WB;Chang, KY;Lee, JS;Liou, JP;Su, RY;Cheng, SM;Hwang, DY;Kikkawa, U;Hsu, TI;Wang, CY;Chang, WC;Chen, PY;Chuang, JY
國家衛生研究院 2021-09-28 Histone deacetylase 6 acts upstream of DNA damage response activation to support the survival of glioblastoma cells Yang, WB;Wu, AC;Hsu, TI;Liou, JP;Lo, WL;Chang, KY;Chen, PY;Kikkawa, U;Yang, ST;Kao, TJ;Chen, RM;Chang, WC;Ko, CY;Chuang, JY
國家衛生研究院 2021-09 Suppression of extracellular vesicle VEGF-C-mediated lymphangiogenesis and pancreatic cancer early dissemination by a selective HDAC1/2 inhibitor Wang, CA;Li, CF;Huang, RC;Li, YH;Liou, JP;Tsai, SJ
國家衛生研究院 2020-04-24 Increased activation of HDAC1/2/6 and Sp1 underlies therapeutic resistance and tumor growth in glioblastoma Yang, WB;Hsu, CC;Hsu, TI;Liou, JP;Chang, KY;Chen, PY;Liu, JJ;Yang, ST;Wang, JY;Yeh, SH;Chen, RM;Chang, WC;Chuang, JY
國家衛生研究院 2020-02-01 Protective effects of 10,11-dihydro-5H-dibenzo[b,f]azepine hydroxamates on vascular cognitive impairment Kaur, N;Fang, YC;Lee, HY;Singh, A;Nepali, K;Lin, MH;Yeh, TK;Lai, MJ;Chan, L;Tu, YK;Banerjee, S;Hu, CJ;Liou, JP
國家衛生研究院 2019-02-21 Synthesis and evaluation of novel 7H-pyrrolo-[2,3-d]pyrimidine derivatives as potential anticancer agents Liu, YM;Chen, CH;Yeh, TK;Liou, JP
國家衛生研究院 2019-01-15 1-Arylsulfonyl indoline-benzamides as a new antitubulin agents, with inhibition of histone deacetylase Lai, MJ;Ojha, R;Lin, MH;Liu, YM;Lee, HY;Lin, TE;Hsu, KC;Chang, CY;Chen, MC;Nepali, K;Chang, JY;Liou, JP
國家衛生研究院 2018-08-23 5-aroylindoles act as selective histone deacetylase 6 inhibitors ameliorating alzheimer's disease phenotypes Lee, HY;Fan, SJ;Huang, FI;Chao, HY;Hsu, KC;Lin, TE;Yeh, TK;Lai, MJ;Li, YH;Huang, HL;Yang, CR;Liou, JP
國家衛生研究院 2018-08-04 Upregulation of Znf179 acetylation by SAHA protects cells against oxidative stress Wu, CC;Lee, PT;Kao, TJ;Chou, SY;Su, RY;Lee, YC;Yeh, SH;Liou, JP;Hsu, TI;Su, TP;Chuang, CK;Chang, WC;Chuang, JY
國家衛生研究院 2018-06-15 2-Aroylquinoline-5,8-diones as potent anticancer agents displaying tubulin and heat shock protein 90 (HSP90) inhibition [Erratum: Organic and Biomolecular Chemistry. 2016 Jan;14(2):716-723.] Nepali, K;Kumar, S;Huang, HL;Kuo, FC;Lee, CH;Kuo, CC;Yeh, TK;Li, YH;Chang, JY;Liou, JP;Lee, HY
國家衛生研究院 2018-03-28 Novel microtubule inhibitor MPT0B098 inhibits hypoxia-induced epithelial-to-mesenchymal transition in head and neck squamous cell carcinoma Tsai, IT;Kuo, CC;Liou, JP;Chang, JY
國家衛生研究院 2017-08-12 Specificity protein 1-modulated superoxide dismutase 2 enhances temozolomide resistance in glioblastoma, which is independent of O6-methylguanine-DNA methyltransferase Chang, KY;Hsu, TI;Hsu, CC;Tsai, SY;Liu, JJ;Chou, SW;Liu, MS;Liou, JP;Ko, CY;Chen, KY;Hung, JJ;Chang, WC;Chuang, CK;Kao, TJ;Chuang, JY
國家衛生研究院 2017-08 Hypoxia-induced downregulation of DUSP-2 phosphatase drives colon cancer stemness Hou, PC;Li, YH;Lin, SC;Lin, SC;Lee, JC;Lin, BW;Liou, JP;Chang, JY;Kuo, CC;Liu, YM;Sun, HS;Tsai, SJ
國家衛生研究院 2016-11-18 Suberoylanilide hydroxamic acid represses glioma stem-like cells Hsu, CC;Chang, WC;Hsu, TI;Liu, JJ;Yeh, SH;Wang, JY;Liou, JP;Ko, CY;Chang, KY;Chuang, JY
國家衛生研究院 2016-07-01 MPT0B098, a microtubule inhibitor, suppresses JAK2/STAT3 signaling pathway through modulation of SOCS3 stability in oral squamous cell carcinoma Peng, HY;Cheng, YC;Hsu, YM;Wu, GH;Kuo, CC;Liou, JP;Chang, JY;Jin, SC;Shiah, SG
國家衛生研究院 2016-01 2-Aroylquinoline-5,8-diones as potent anticancer agents displaying tubulin and heat shock protein 90 (HSP90) inhibition Nepali, K;Kumar, S;Huang, HL;Kuo, FC;Lee, CH;Kuo, CC;Yeh, TK;Li, YH;Chang, JY;Liou, JP;Lee, HY
國家衛生研究院 2015-08 Antimitotic and antivascular activity of heteroaroyl-2-hydroxy-3,4,5-trimethoxybenzenes Lee, HY;Chang, CY;Lai, MJ;Chuang, HY;Kuo, CC;Chang, CY;Chang, JY;Liou, JP

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