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Institution Date Title Author
臺北醫學大學 2014 Denbinobin upregulates miR-146a expression and attenuates IL-1β-induced upregulation of ICAM-1 and VCAM-1 expressions in osteoarthritis fibroblast-like synoviocytes Yang, CR;Shih, KS;Liou, JP;Wu, YW;Hsieh, IN;Lee, HY;Lin, TC;Wang, JH
臺北醫學大學 2014 In vitro and in vivo anti-tumour effects of MPT0B014, a novel derivative aroylquinoline, and in combination with erlotinib in human non-small-cell lung cancer cells Tsai, AC;Pai, HC;Wang, CY;Liou, JP;Teng, CM;Wang, JC;Pan, SL
臺北醫學大學 2014 Indole-3-ethylsulfamoylphenylacrylamides: Potent histone deacetylase inhibitors with anti-inflammatory activity Mehndiratta, S;Hsieh, YL;Liu, YM;Wang, AW;Lee, HY;Liang, LY;Kumar, S;Teng, CM;CR*, Yang;Liou, JP*.
臺北醫學大學 2014 Intermediary Metabolite Precursor Dimethyl-2-Ketoglutarate Stabilizes Hypoxia-Inducible Factor-1α by Inhibiting Prolyl-4-Hydroxylase PHD2 Hou, P;Kuo, CY;Cheng, CT;Liou, JP;Ann, DK;Chen, Q
臺北醫學大學 2014 K20E, an oxidative-coupling compound of methyl caffeate, exhibits anti-angiogenic activities through down-regulations of VEGF and VEGF receptor-2 Lee, HY;Wang, LT;Li, YH;Pan, SL;Chen, YL;Teng, CM;Liou, JP
臺北醫學大學 2014 Orally active microtubule-targeting agent, MPT0B271, for the treatment of human non-small cell lung cancer, alone and in combination with erlotinib Tsai, AC;Wang, CY;Liou, JP;Pai, HC;Hsiao, CJ;Chang, JY;Wang, JC;Teng, CM;Pan, SL.
臺北醫學大學 2014 Preclinical anti-arthritic study and pharmacokinetic properties of a potent histone deacetylase inhibitor MPT0G009 Hsieh, IN;Liou, JP;Lee, HY;Lai, MJ;Li, YH;Yang, CR
臺北醫學大學 2014 Tubulin inhibitors: a patent review Liu, YM;Chen, HL;Lee, HY;Liou, JP
臺北醫學大學 2014 A novel action mechanism for MPT0G013, a derivative of arylsulfonamide, inhibits tumor angiogenesis through up-regulaiton of TIMP3 expression Wang, CY;Liou, JP;Tsai, AC;Lai, MJ;Liu, YM;Lee, HY;Wang, JC;SL*, Pan;CM*, Teng
臺北醫學大學 2014 In vitro and in vivo antitumor effects of MPT0B014, a novel derivative aroylquinoline, and in combination with erlotinib in human non-small-cell lung cancer cells Tsai, AC;Pai, HC;Wang, CY;Liou, JP;Teng, CM;Wang, JC;Pan, SL
國家衛生研究院 2013-10 Histone deacetylase inhibition improved cardiac functions with direct antifibrotic activity in heart failure Kao, YH;Liou, JP;Chung, CC;Lien, GS;Kuo, CC;Chen, SA;Chen, YJ
國家衛生研究院 2013-09 MPT0B169, a new tubulin inhibitor, inhibits cell growth and induces G2/M Arrest in nonresistant and paclitaxel-resistant cancer cells Lee, WH;Liu, HE;Chang, JY;Liou, JP;Huang, HM
國家衛生研究院 2013-09 MPT0B098, a novel microtubule inhibitor that destabilizes the hypoxia-inducible factor-1α mrna through decreasing nuclear-cytoplasmic translocation of RNA-binding protein HuR [Erratum: Molecular Cancer Therapeutics. 2013 Jul;12(7):1202-1212.] Cheng, YC;Liou, JP;Kuo, CC;Lai, WY;Shih, KH;Chang, CY;Pan, WY;Tseng, JT;Chang, JY
國家衛生研究院 2013-09 Furanylazaindoles: Potent anticancer agents in vitro and in vivo Lee, HY;Pan, SL;Su, MC;Liu, YM;Kuo, CC;Chang, YT;Wu, JS;Nien, CY;Mehndiratta, S;Chang, CY;Wu, SY;Lai, MJ;Chang, JY;Liou, JP
國家衛生研究院 2013-07-08 1-arylsulfonyl-5-(N-hydroxyacrylamide)indolines histone deacetylase inhibitors are potent cytokine release suppressors Lee, HY;Yang, CR;Lai, MJ;Huang, HL;Hsieh, YL;Liu, YM;Yeh, TK;Li, YH;Mehndiratta, S;Teng, CM;Liou, JP
國家衛生研究院 2013-07-08 Inside Cover: 1-arylsulfonyl-5-(N-hydroxyacrylamide)indolines histone deacetylase inhibitors are potent cytokine release suppressors(ChemBioChem 10/2013) Lee, HY;Yang, CR;Lai, MJ;Huang, HL;Hsieh, YL;Liu, YM;Yeh, TK;Li, YH;Mehndiratta, S;Teng, CM;Liou, JP
國家衛生研究院 2013-07 MPT0B098, a novel microtubule inhibitor that destabilizes the hypoxia-inducible factor-1 alpha mRNA through decreasing nuclear-cytoplasmic translocation of RNA-binding protein HuR Cheng, YC;Liou, JP;Kuo, CC;Lai, WY;Shih, KH;Chang, CY;Pan, WY;Tseng, JT;Chang, JY
國家衛生研究院 2013-04 MPT0G066, a novel microtubule-destabilizing agent, induces cell apoptosis and potentiates antineoplastic effects of cisplatin in human ovarian cancer cells in vitro and in vivo Chen, CH;Li, YC;Chang, LH;Liou, JP;Pan, SL;Teng, CM
國家衛生研究院 2013-03-12 A novel synthetic microtubule inhibitor, MPT0B214 exhibits antitumor activity in human tumor cells through mitochondria-dependent intrinsic pathway Chiang, NJ;Lin, CI;Liou, JP;Kuo, CC;Chang, CY;Chen, LT;Chang, JY
國家衛生研究院 2013-02 Azatyrosinamides: Novel RAS-related anticancer agents Wang, CL;Lee, O;Huang, CF;Li, EIC;Teng, CM;Pan, SL;Lian, JF;Chang, FS;Liou, JP;Wang, HP
臺北醫學大學 2013 Di- and Tripeptide Mimetic Prodrugs of Levodopa: Systemic and Brain Bioavailability of D-Phenylglycine-L-Dopa, a Sustained Dopamine Releasing Prodrug CL, Wang;YB, Fan;Lee, SE;Lian, JF;Liou, JP;Wang, HP
臺北醫學大學 2013 Histone deacetylase inhibition improved cardiac functions with direct antifibrotic activity in heart failure Kao, YH;Liou, JP;Chung, CC;Lien, GS;Kuo, CC;Chen, SA;Chen, YJ
臺北醫學大學 2013 Di- and Tripeptide Mimetic Prodrugs of Levodopa: Systemic and Brain Bioavailability of D-Phenylglycine-L-Dopa, a Sustained Dopamine Releasing Prodrug Wang, CL;Fan, YB;Lee, SE;Lian, JF;Liou, JP;Wang, HP
臺北醫學大學 2013 Evaluation of the safety and efficacy of warfarin in Taiwanese patients Kuo, LN;Liou, JP;Chen, HY;Chiang, YC;Wu, MT
臺北醫學大學 2013 A novel synthetic microtubule inhibitor, MPT0B214 exhibits antitumor activity in human tumor cells through mitochondria-dependent intrinsic pathway Chiang, NJ;Lin, CI;Liou, JP;Kuo, CC;Chang, CY;Chen, LT;Chang, JY
臺北醫學大學 2013 MPT0B098, a novel microtubule inhibitor that destabilizes the hypoxia-inducible factor-1α mRNA through decreasing nuclear-cytoplasmic translocation of RNA-binding protein HuR Cheng, YC;Liou, JP;Kuo, CC;Lai, WY;Shih, KH;Chang, CY;Pan, WY;Tseng, JT;Chang, JY.
國家衛生研究院 2012-12 Application of Suzuki arylation, Sonogashira ethynylation and Rosenmund-von Braun cyanation in the exploration of substitution effects on the anticancer activity of 2-aroylquinolines Lee, HY;Lee, LW;Nien, CY;Kuo, CC;Lin, PY;Chang, CY;Chang, JY;Liou, JP
國家衛生研究院 2012-08-22 Anticancer activity of MPT0E028, a novel potent histone deacetylase inhibitor, in human colorectal cancer HCT116 cells in vitro and in vivo Huang, HL;Lee, HY;Tsai, AC;Peng, CY;Lai, MJ;Wang, JC;Pan, SL;Teng, CM;Liou, JP
國家衛生研究院 2012-04 Synthesis and biological evaluation of 1-Arylsulfonyl-5-(N-hydroxyacrylamide)indoles as potent histone deacetylase inhibitors with antitumor activity in vivo Lai, MJ;Huang, HL;Pan, SL;Liu, YM;Peng, CY;Lee, HY;Yeh, TK;Huang, PH;Teng, CM;Chen, CS;Chuang, HY;Liou, JP
國家衛生研究院 2012-03-06 Indole compounds Hsieh, HP;Liou, JP;Chang, JY;Chang, CW
中國醫藥大學 2012-03 Synthesis and Biological Evaluation of 1-Arylsulfonyl-5-(N-hydroxyacrylamide)indoles as Potent Histone Deacetylase Inhibitors with Antitumor Activity in Vivo (Lai MJ);(Huang HL); (Pan SL);(Liu YM);彭婕妤(Chieh-Yu Peng);(Lee HY);(Yeh TK);(Huang PH); (Teng CM);(Chen CS);(Chuang HY);(Liou JP)*
臺北醫學大學 2012 Anti-Arthritic Effects of Magnolol in Human Interleukin 1b-Stimulated Fibroblast-Like Synoviocytes and in a Rat Arthritis Model Wang, JH;Shih, KS;Liou, JP;Wu, YM;ASY, Chang;Wang, KL;Tsai, CL;Yang, CR
臺北醫學大學 2012 ARYL SUBSTITUTED SULFONAMIDE COMPOUNDS AND THEIR USE AS ANTICANCER AGENTS Liou, JP;Chang, JY
國家衛生研究院 2011-12-22 5-Amino-2-aroylquinolines as highly potent tubulin polymerization inhibitors. Part 2. The impact of bridging groups at position C-2 Lee, HY;Chang, JY;Nien, CY;Kuo, CC;Shih, KH;Wu, CH;Chang, CY;Lai, WY;Liou, JP
國家衛生研究院 2011-09 Synthesis and biological evaluation of 1-(4′-Indolyl and 6′-Quinolinyl) indoles as a new class of potent anticancer agents Lai, MJ;Chang, JY;Lee, HY;Kuo, CC;Lin, MH;Hsieh, HP;Chang, CY;Wu, JS;Wu, SY;Shey, KS;Liou, JP
國家衛生研究院 2011-04-28 Scaffold-hopping strategy: Synthesis and biological evaluation of 5,6-Fused bicyclic heteroaromatics to identify orally bioavailable anticancer agents Tung, YS;Coumar, MS;Wu, YS;Shiao, HY;Chang, JY;Liou, JP;Shukla, P;Chang, CW;Chang, CY;Kuo, CC;Yeh, TK;Lin, CY;Wu, JS;Wu, SY;Liao, CC;Hsieh, HP
國家衛生研究院 2011-04-06 Indole compounds as inhibitors of tubulin polymerisation for the treatment of angiogenesis related disorders Hsieh, HP;Chang, JY;Liou, JP;Chang, CW
國家衛生研究院 2011-04 Concise syntheses of N-aryl-5,6,7-trimethoxyindoles as antimitotic and vascular disrupting agents: application of the copper-mediated Ullmann-type arylation Lee, HY;Chang, JY;Chang, LY;Lai, WY;Lai, MJ;Shih, KH;Kuo, CC;Chang, CY;Liou, JP
國家衛生研究院 2011-04 MPT0B098, a novel microtubule inhibitor, displays potent anti-angiogenic activity via destabilizing hypoxia-inducible factor-1alpha mRNA Cheng, YC;Liou, JP;Lai, WY;Chang, CY;Pan, WY;Kuo, CC;Chang, JY
國家衛生研究院 2011-03-07 Synthesis and biological evaluation of 4-aroyl-6,7,8-trimethoxyquinolines as a novel class of anticancer agents Hsieh, CC;Lee, HY;Nien, CY;Kuo, CC;Chang, CY;Chang, JY;Liou, JP
國家衛生研究院 2011-03-07 2-Amino-3,4,5-Trimethoxybenzophenones as Potent Tubulin Polymerization Inhibitors Chuang, HY;Chang, JY;Lai, MJ;Kuo, CC;Lee, HY;Hsieh, HP;Chen, YJ;Chen, LT;Pan, WY;Liou, JP
高雄醫學大學 2011 2-amino-3,4,5-trimethoxybenzophenones as potent tubulin polymerization inhibitors.  陳立宗; Chuang HY;Chang JY;Lai MJ;Kuo CC;Lee HY;Hsieh HP;Chen YJ;Chen LT;Pan WY;Liou JP. 
臺北醫學大學 2011 2-Amino-3,4,5-Trimethoxybenzophenones as Potent Tubulin Polymerization Inhibitors Chuang, HY;Chang, JY;Lai, MJ;Kuo, CC;Lee, HY;Hsieh, HP;Chen, YJ;Chen, LT;Pan, WY;Liou, JP
臺北醫學大學 2011 5-Amino-2-aroylquinolines as Highly Potent Tubulin Polymerization Inhibitors Lee, HY;Chang, JY;Nien, CY;Kuo, CC;Shih, KH;Wu, CH;Chang, CY;Lai, WY;Liou, JP
臺北醫學大學 2011 Concise syntheses of N-aryl-5,6,7-trimethoxyindoles as antimitotic and vascular disrupting agents: application of the copper-mediated Ullmann-type arylation Lee, HY;Chang, JY;Chang, LY;Lai, WY;Lai, MJ;Shih, KH;Kuo, CC;Chang, CY;Liou, JP
臺北醫學大學 2011 Synthesis and Biological Evaluation of 1-(4’-Indolyl and 6’-Quinolinyl)indoles as a New Class of Potent Anticancer Agents Lia, MJ;Chang, JY;Lee, HY;Kuo, CC;Lin, MH;Hsieh, HP;Chang, CY;Wu, JS;Wu, SY;Shey, KS;Liou, JP
臺北醫學大學 2011 Synthesis and biological evaluation of 1-(40-Indolyl and 60-Quinolinyl) indoles as a new class of potent anticancer agents. Lai, MJ;Chang, JY;Lee, HY;Kuo, CC;Lin, MH;Hsieh, HP;Chang, CY;Wu, JS;Wu, SY;Shey;KS;Liou, JP
臺北醫學大學 2011 Synthesis and Biological Evaluation of 4-Aroyl-6,7,8-Trimethoxyquinolines as a Novel Class of Anticancer Agents Hsieh, CC;Lee, HY;Nien, CY;Kuo, CC;Chang, CY;Chang, JY;Liou, JP
國家衛生研究院 2010-12-01 抗肿瘤化合物 Hsieh, HP;Chao, YS;Liou, JP;Chang, JY;Tung, YS
國家衛生研究院 2010-08 Synthesis and biological evaluation of 7-arylindoline-1-benzenesulfonamides as a novel class of potent anticancer agents Chang, JY;Lai, MJ;Chang, YT;Lee, HY;Cheng, YC;Kuo, CC;Su, MC;Chang, CY;Liou, JP

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