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机构 日期 题名 作者
國家衛生研究院 2011-04-28 Scaffold-hopping strategy: Synthesis and biological evaluation of 5,6-Fused bicyclic heteroaromatics to identify orally bioavailable anticancer agents Tung, YS;Coumar, MS;Wu, YS;Shiao, HY;Chang, JY;Liou, JP;Shukla, P;Chang, CW;Chang, CY;Kuo, CC;Yeh, TK;Lin, CY;Wu, JS;Wu, SY;Liao, CC;Hsieh, HP
國家衛生研究院 2011-04-06 Indole compounds as inhibitors of tubulin polymerisation for the treatment of angiogenesis related disorders Hsieh, HP;Chang, JY;Liou, JP;Chang, CW
國家衛生研究院 2011-04 Concise syntheses of N-aryl-5,6,7-trimethoxyindoles as antimitotic and vascular disrupting agents: application of the copper-mediated Ullmann-type arylation Lee, HY;Chang, JY;Chang, LY;Lai, WY;Lai, MJ;Shih, KH;Kuo, CC;Chang, CY;Liou, JP
國家衛生研究院 2011-04 MPT0B098, a novel microtubule inhibitor, displays potent anti-angiogenic activity via destabilizing hypoxia-inducible factor-1alpha mRNA Cheng, YC;Liou, JP;Lai, WY;Chang, CY;Pan, WY;Kuo, CC;Chang, JY
國家衛生研究院 2011-03-07 Synthesis and biological evaluation of 4-aroyl-6,7,8-trimethoxyquinolines as a novel class of anticancer agents Hsieh, CC;Lee, HY;Nien, CY;Kuo, CC;Chang, CY;Chang, JY;Liou, JP
國家衛生研究院 2011-03-07 2-Amino-3,4,5-Trimethoxybenzophenones as Potent Tubulin Polymerization Inhibitors Chuang, HY;Chang, JY;Lai, MJ;Kuo, CC;Lee, HY;Hsieh, HP;Chen, YJ;Chen, LT;Pan, WY;Liou, JP
高雄醫學大學 2011 2-amino-3,4,5-trimethoxybenzophenones as potent tubulin polymerization inhibitors.  陳立宗; Chuang HY;Chang JY;Lai MJ;Kuo CC;Lee HY;Hsieh HP;Chen YJ;Chen LT;Pan WY;Liou JP. 
臺北醫學大學 2011 2-Amino-3,4,5-Trimethoxybenzophenones as Potent Tubulin Polymerization Inhibitors Chuang, HY;Chang, JY;Lai, MJ;Kuo, CC;Lee, HY;Hsieh, HP;Chen, YJ;Chen, LT;Pan, WY;Liou, JP
臺北醫學大學 2011 5-Amino-2-aroylquinolines as Highly Potent Tubulin Polymerization Inhibitors Lee, HY;Chang, JY;Nien, CY;Kuo, CC;Shih, KH;Wu, CH;Chang, CY;Lai, WY;Liou, JP
臺北醫學大學 2011 Concise syntheses of N-aryl-5,6,7-trimethoxyindoles as antimitotic and vascular disrupting agents: application of the copper-mediated Ullmann-type arylation Lee, HY;Chang, JY;Chang, LY;Lai, WY;Lai, MJ;Shih, KH;Kuo, CC;Chang, CY;Liou, JP
臺北醫學大學 2011 Synthesis and Biological Evaluation of 1-(4’-Indolyl and 6’-Quinolinyl)indoles as a New Class of Potent Anticancer Agents Lia, MJ;Chang, JY;Lee, HY;Kuo, CC;Lin, MH;Hsieh, HP;Chang, CY;Wu, JS;Wu, SY;Shey, KS;Liou, JP
臺北醫學大學 2011 Synthesis and biological evaluation of 1-(40-Indolyl and 60-Quinolinyl) indoles as a new class of potent anticancer agents. Lai, MJ;Chang, JY;Lee, HY;Kuo, CC;Lin, MH;Hsieh, HP;Chang, CY;Wu, JS;Wu, SY;Shey;KS;Liou, JP
臺北醫學大學 2011 Synthesis and Biological Evaluation of 4-Aroyl-6,7,8-Trimethoxyquinolines as a Novel Class of Anticancer Agents Hsieh, CC;Lee, HY;Nien, CY;Kuo, CC;Chang, CY;Chang, JY;Liou, JP
國家衛生研究院 2010-12-01 抗肿瘤化合物 Hsieh, HP;Chao, YS;Liou, JP;Chang, JY;Tung, YS
國家衛生研究院 2010-08 Synthesis and biological evaluation of 7-arylindoline-1-benzenesulfonamides as a novel class of potent anticancer agents Chang, JY;Lai, MJ;Chang, YT;Lee, HY;Cheng, YC;Kuo, CC;Su, MC;Chang, CY;Liou, JP
國家衛生研究院 2010-07 Antiangiogenic Activities and Cisplatin-combined Antitumor Activities of BPR0L075 Chen, CP;Hu, CB;Yeh, KC;Song, JS;Yeh, TK;Tung, FF;Hwang, LL;Tseng, HY;Huang, YC;Shy, HS;Hsieh, SH;Shen, CC;Wang, HS;Hsieh, HP;Liou, JP;Chao, YS;Chen, CT
國家衛生研究院 2010-03-11 5-Amino-2-Aroylquinolines as Highly Potent Tubulin Polymerization Inhibitors Nien, CY;Chen, YC;Kuo, CC;Hsieh, HP;Chang, CY;Wu, JS;Wu, SY;Liou, JP;Chang, JY
臺北醫學大學 2010 5-Amino-2-Aroylquinolines as Highly Potent Tubulin Polymerization Inhibitors Nien, CY;Chen, YC;Kuo, CC;Hsieh, HP;Chang, CY;Wu, JS;Wu, SY;Liou, JP;Chang, JY
國家衛生研究院 2009-12-15 Indole compounds Hsieh, HP;Liou, JP;Chang, JY;Chang, CW
國家衛生研究院 2009-12-01 芳香羰吲哚化合物 Hsieh, HP;Liou, JP;Chang, JY;Chang, CW
國家衛生研究院 2009-08-13 Synthesis and evaluation of 3-aroylindoles as anticancer agents: Metabolite approach Wu, YS;Coumar, MS;Chang, JY;Sun, HY;Kuo, FM;Kuo, CC;Chen, YJ;Chang, CY;Hsiao, CL;Liou, JP;Chen, CP;Yao, HT;Chiang, YK;Tan, UK;Chen, CT;Chu, CY;Wu, SY;Yeh, TK;Lin, CY;Hsieh, HP
中國醫藥大學 2009-08 Synthesis and Evaluation of 3-Aroylindoles as Anticancer Agents: Metabolite Approach. (Wu YS); (Coumar MS); (Chang JY); (Sun HY); (Kuo FM); (Kuo CC); (Chen YJ); (Chang CY); (Hsiao CL); (Liou JP); (Chen CP); 姚賢宗(Hsien-Tsung Yao); (Chiang YK); (Tan UK); (Chen CT); (Chu CY); (Wu SY); (Yeh TK); (Lin CY); (Hsieh HP)*
國家衛生研究院 2009-05-05 Indole compounds Hsieh, HP;Liou, JP;Chang, JY;Chang, CW
國家衛生研究院 2009-04-17 Synthesis and structure-activity relationships of 1-benzyl-4,5,6-trimethoxyindoles as a novel class of potent antimitotic agents Lai, MJ;Kuo, CC;Yeh, TK;Hsieh, HP;Chen, LT;Pan, WY;Hsu, KY;Chang, JY;Liou, JP
國家衛生研究院 2008-12-25 Synthesis and structure-activity relationships of 2-amino-1-aroylnaphthalene and 2-hydroxy-1-aroylnaphthalenes as potent antitubulin agents Reddy, GR;Kuo, CC;Tan, UK;Coumar, MS;Chang, CY;Chiang, YK;Lai, MJ;Yeh, JY;Wu, SY;Chang, JY;Liou, JP;Hsieh, HP
國家衛生研究院 2008-11-25 Anti-tumor compounds Hsieh, HP;Chao, YS;Liou, JP;Chang, JY;Tung, YS
國家衛生研究院 2008-07-24 Discovery of 4-amino and 4-hydroxy-1-aroylindoles as potent tubulin polymerization inhibitors Liou, JP; Wu, ZY; Kuo, CC; Chang, CY; Lu, PY; Chen, CM; Hsieh, HP; Chang, JY
國家衛生研究院 2008-05-01 抗腫瘤化合物 Hsieh, HP;Liou, JP;Chang, JY;Tung, YS;Chao, YS
臺北醫學大學 2008 Discovery of 4-Amino and 4-Hydroxy-1-Aroylindoles as Potent Tubulin Polymerization Inhibitors 劉景平; Liou JP; Wu ZY; Kuo CC; Chang CY; Lu PY; Chen CM; Hsieh HP; Chang JY
臺北醫學大學 2008 Synthesis and Structure-Activity Relationships of 2-Amino and 2-Hydroxy-1-Aroylnaphthalenes as Potent Antitubulin Agents 劉景平; Reddy GR; Kuo CC; Tan UK; Coumar MS; Chang CY; Lai MJ; Wu SY; Chang JY; Liou JP; Hsieh HP
國家衛生研究院 2007-10 A novel oral indoline-sulfonamide agent, N-[1-(4-Methoxy-benzenesulfonyl)-2,3-dihydro-1H-indol-7-yl]-Isonicotinamide (J30), exhibits potent activity against human cancer cells in vitro and in vivo through the disruption of microtubule Liou, JP; Hsu, KS; Kuo, CC; Chang, CY; Chang, JY
國家衛生研究院 2007-09-06 4-and 5-aroylindoles as novel classes of potent antitubulin agents Liou, JP; Wu, CY; Hsieh, HP; Chang, CY; Chen, CM; Kuo, CC; Chang, JY
國家衛生研究院 2007-07 A novel oral indoline-sulfonamide derivative, J30, exhibits potent activity against human cancer cells both in in vitro and in vivo through disruption of microtubule Chang, JY;Liou, JP
臺北醫學大學 2007 2-Methoxyestradiol attenuates phosphatidylinositol 3-kinase/Akt pathway-mediated metastasis of gastric cancer. 劉景平; Lin HL; Yang MH; Wu CW; Chen PM; Yang YP; Chu YR; Kao CL; Ku HH; Lo JF; Liou JP; Chi CW; Chi
臺北醫學大學 2007 4- and 5-Aroylindoles as Novel Classes of Potent Antitubulin Agents. 劉景平; Liou JP; Wu CY; Hsieh HP; Chang CY; Chen CM; Kuo CC; Chang JY
臺北醫學大學 2007 A novel oral indoline-sulfonamide agent; J30; exhibits potent activity against human cancer cells in vitro and in vivo through the disruption of microtubule. 劉景平; Liou JP; Hsu KS; Kuo CC; Chang CY; Chang JY;
臺北醫學大學 2007 Combretastatin A-4 Induced Differential Cytotoxicity and Reduced Metastatic Ability by Inhibition of AKT Function in Hunan Gastric Cancer Cells. 劉景平; Lin HL; Chiou SH; Wu CW; Lin WB; Chen LH; Yang YP; Tsai ML; Uen YH; Liou JP; Chi CW
國家衛生研究院 2006-11-16 7-aroyl-aminoindoline-1-sulfonamides as a novel class of potent antitubulin agents Chang, JY; Hsieh, HP; Chang, CY; Hsu, KS; Chiang, YF; Chen, CM; Kuo, CC; Liou, JP
國家衛生研究院 2006-10-19 2-amino and 2 '-aminocombretastatin derivatives as potent antimitotic agents Chang, JY; Yang, MF; Chang, CY; Chen, CM; Kuo, CC; Liou, JP
國家衛生研究院 2006-10 Structure-activity relationship studies of 3-aroylindoles as potent antimitotic agents Liou, JP;Mahindroo, N;Chang, CW;Guo, FM;Lee, SWH;Tan, UK;Yeh, TK;Kuo, CC;Chang, YW;Lu, PH;Tung, YS;Lin, KT;Chang, JY;Hsieh, HP
國家衛生研究院 2006-05 Antitubulin agents for the treatment of cancer - a medicinal chemistry update Mahindroo, N; Liou, JP; Chang, JY; Hsieh, HP
臺北醫學大學 2006 2-Amino and 2’-Aminocombretastatin Derivatives as Potential Antimitotic Agent 陳繼明; 劉景平; Chang JY; Yang MF; Chang CY; Chen CM; Kuo CC; Liou JP
臺北醫學大學 2006 7-Aroyl-aminoindoline-1-sulfonamides as a Novel Class of Potent Antitubulin Agents 劉景平; 陳繼明; Chang JY; Hsieh HP; Chang CY; Hsu KS; Chiang YF; Chen CM; Kuo CC; Liou JP*
臺北醫學大學 2006 Antitubulin agents for the treatment of cancer-a medicinal chemistry update 劉景平; Mahindroo N; Liou JP; Chang JY; Hsieh HP
臺北醫學大學 2006 Structure-Activity Relationship Studies of 3-Aroylindoles as Potent Antimitotic Agents 劉景平; Liou JP; Mahindroo N; Chang CW; Guo FM; Lee SW; Yeh TK; Tan UK; Kuo CC; Chang YW; Lu PH; Tung YS;
國家衛生研究院 2005-08-23 Indole compounds Hsieh, HP;Liou, JP;Chang, JY;Chang, CW
國家衛生研究院 2005-05 Pharmaceutical design of antimitotic agents based on combretastatins Hsieh, HP;Liou, JP;Mahindroo, N
臺北醫學大學 2005 A concise synthesis of denbinobin 陳繼明; 劉景平; Wang YC; Lin CH; Chen CM; Liou JP
臺北醫學大學 2005 A concise synthesis of denbinobin. 林建煌; Wang YC; Lin CH; Chen CM; Liou JP
國家衛生研究院 2004-09 Drug design of BPR0L075 as an anticancer agent Hsieh, HP;Liou, JP;Chang, CW;Kuo, CC;Chang, YL;Kuo, FM;Tseng, HY;Pan, WY;Chen, CP;Yang, YN;Chen, CT;Lee, SJ;Chang, JY

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