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机构 日期 题名 作者
國家衛生研究院 2024-06-19 pH-responsive beta-glucans-complexed mRNA in LNPs as an oral vaccine for enhancing cancer immunotherapy Luo, PK;Ho, HM;Chiang, MC;Chu, LA;Chuang, YH;Lyu, PC;Hu, IC;Chang, WA;Peng, SY;Jayakumar, J;Chen, HL;Huang, MH;Sung, HW
國家衛生研究院 2023-02-11 PW06 triggered fas-FADD to induce apoptotic cell death in human pancreatic carcinoma MIA PaCa-2 cells through the activation of the caspase-mediated pathway Huang, YP;Hsia, TC;Yeh, CA;Ma, YS;Hsu, SY;Liu, YC;Lyu, PC;Lai, KC;Peng, SF;Lien, JC;Hsieh, WT
國家衛生研究院 2021-06-17 LINC01348 suppresses hepatocellular carcinoma metastasis through inhibition of SF3B3-mediated EZH2 pre-mRNA splicing Lin, YH;Wu, MH;Liu, YC;Lyu, PC;Yeh, CT;Lin, KH
國家衛生研究院 2021-06-17 Ergosta-7, 9 (11), 22-trien-3Beta-ol interferes with lps docking to lbp, cd14, and tlr4/md-2 co-receptors to attenuate the nf-kappab inflammatory pathway in vitro and drosophila Hsieh, WT;Hsu, MH;Lin, WJ;Xiao, YC;Lyu, PC;Liu, YC;Lin, WY;Kuo, YH;Chung, JG
國家衛生研究院 2021-0227 Imperatorin interferes with LPS binding to the TLR4 co-receptor and activates the Nrf2 antioxidative pathway in RAW264.7 murine macrophage cells Huang, MH;Lin, YH;Lyu, PC;Liu, YC;Chang, YS;Chung, JG;Lin, WY;Hsieh, WT
國家衛生研究院 2020-12-31 Cafestol inhibits high-glucose-induced cardiac fibrosis in cardiac fibroblasts and type 1-like diabetic rats Liu, JC;Chen, PY;Hao, WR;Liu, YC;Lyu, PC;Hong, HJ
國家衛生研究院 2020-10-12 Structural insights into the active site formation of dusp22 in n-loop-containing protein tyrosine phosphatases Lai, CH;Chang, CC;Chuang, HC;Tan, TH;Lyu, PC
國家衛生研究院 2020-08-14 An essential role of acetyl coenzyme a in the catalytic cycle of insect arylalkylamine N-acetyltransferase Wu, CY;Hu, IC;Yang, YC;Ding, WC;Lai, CH;Lee, YZ;Liu, YC;Cheng, HC;Lyu, PC
國家衛生研究院 2020-08-09 Antimicrobial peptide TP4 targets mitochondrial adenine nucleotide translocator 2 Su, BC;Liu, YC;Ting, CH;Lyu, PC;Chen, JY
國家衛生研究院 2019-12 The ligand-mediated affinity of brain-type fatty acid-binding protein for membranes determines the directionality of lipophilic cargo transport Cheng, YY;Huang, YF;Lin, HH;Chang, WW;Lyu, PC
國家衛生研究院 2019-08-20 MAP4K3/GLK promotes lung cancer metastasis by phosphorylating and activating IQGAP1 Chuang, HC;Chang, CC;Teng, CF;Hsueh, CH;Chiu, LL;Hsu, PM;Lee, MC;Hsu, CP;Chen, YR;Liu, YC;Lyu, PC;Tan, TH
國家衛生研究院 2019-03-20 TNF-alpha-induced miR-450a mediates TMEM182 expression to promote oral squamous cell carcinoma motility Hsing, EW;Shiah, SG;Peng, HY;Chen, YW;Chuu, CP;Hsiao, JR;Lyu, PC;Chang, JY
國家衛生研究院 2018-11-22 Nile tilapia derived antimicrobial peptide TP4 exerts antineoplastic activity through microtubule disruption Ting, CH;Liu, YC;Lyu, PC;Chen, JY
國家衛生研究院 2017-12 Cdc7-Dbf4-mediated phosphorylation of HSP90-S164 stabilizes HSP90-HCLK2-MRN complex to enhance ATR/ATM signaling that overcomes replication stress in cancer Cheng, AN;Fan, CC;Lo, YK;Kuo, CL;Wang, HC;Lien, IH;Lin, SY;Chen, CH;Jiang, SS;Chang, IS;Juan, HF;Lyu, PC;Lee, AYL
國家衛生研究院 2016-09 A clamp-like orientation of basic residues set in a parallelogram is essential for heparin binding Cheng, YY;Cheng, CS;Lee, TR;Chang, WW;Lyu, PC
國家衛生研究院 2016-07 Role of the RAD51-SWI5-SFR1 Ensemble in homologous recombination Su, GC;Yeh, HY;Lin, SW;Chung, CI;Huang, YS;Liu, YC;Lyu, PC;Chi, P
國家衛生研究院 2016-04-12 Pyrazolylamine derivatives reveal the conformational switching between type I and type II binding modes of Anaplastic Lymphoma Kinase (ALK) Tu, CH;Lin, WH;Peng, YH;Hsu, T;Wu, JS;Chang, CY;Lu, CT;Lyu, PC;Shih, C;Jiaang, WT;Wu, SY
國家衛生研究院 2015-12-17 Complete genome sequence of Xanthomonas campestris pv. campestris Strain 17 from Taiwan Liu, YC;Wang, SC;Yu, YJ;Fung, KM;Yang, MT;Tseng, YH;Tsai, SF;Sun, HS;Lyu, PC;Chou, SH
國家衛生研究院 2015-04 The role of miR-450a in oral squamous cell carcinoma carcinogenesis Hsing, EW;Shiah, SG;Hsiao, JR;Lyu, PC;Chang, JY
國立交通大學 2014-12-08T15:41:14Z Fine-grained protein fold assignment by support vector machines using generalized npeptide coding schemes and jury voting from multiple-parameter sets Yu, CS; Wang, JY; Yang, JM; Lyu, PC; Lin, CJ; Hwang, JK
國立交通大學 2014-12-08T15:40:51Z Computation of the protein structure entropy and its applications to protein folding processes Chan, CH; Lyu, PC; Hwang, JK
國立交通大學 2014-12-08T15:40:14Z Relationship between protein structures and disulfide bonding patterns Chuang, CC; Chen, CY; Yang, JM; Lyu, PC; Hwang, JK
國立交通大學 2014-12-08T15:37:12Z Relationship between local structural entropy and protein thermostability Chan, CH; Liang, HK; Hsiao, NW; Ko, MT; Lyu, PC; Hwang, JK
國家衛生研究院 2013-05 Protein kinase inhibitor design by targeting the Asp-Phe-Gly (DFG) motif: The role of the DFG motif in the design of epidermal growth factor receptor inhibitors Peng, YH;Shiao, HY;Tu, CH;Liu, PM;Hsu, JT;Amancha, PK;Wu, JS;Coumar, MS;Chen, CH;Wang, SY;Lin, WH;Sun, HY;Chao, YS;Lyu, PC;Hsieh, HP;Wu, SY
國家衛生研究院 2011-11-01 Proteomic analysis of gemcitabine-induced drug resistance in pancreatic cancer cells Chen, YW;Liu, JY;Lin, ST;Li, JM;Huang, SH;Chen, JY;Wu, JY;Kuo, CC;Wu, CL;Lu, YC;Chen, YH;Fan, CY;Huang, PC;Law, CH;Lyu, PC;Chou, HC;Chan, HL
國家衛生研究院 2011-06 Mitochondrial proteomics analysis of tumorigenic and metastatic breast cancer markers Chen, YW;Chou, HC;Lyu, PC;Yin, HS;Huang, FL;Chang, WSW;Fan, CY;Tu, IF;Lai, TC;Lin, ST;Lu, YC;Wu, CL;Huang, SH;Chan, HL
國家衛生研究院 2010-10 Structural basis for the improved potency of peroxisome proliferator-activated receptor (PPAR) agonists Peng, YH;Coumar, MS;Leou, JS;Wu, JS;Shiao, HY;Lin, CH;Lin, WH;Lien, TW;Chen, X;Hsu, JT;Chao, YS;Huang, CF;Lyu, PC;Hsieh, HP;Wu, SY
國家衛生研究院 2010-06 Design and synthesis of alpha-ketoamides as cathepsin S inhibitors with potential applications against tumor invasion and angiogenesis Chen, JC;Uang, BJ;Lyu, PC;Chang, JY;Liu, KJ;Kuo, CC;Hsieh, HP;Wang, HC;Cheng, CS;Chang, YH;Chang, MDT;Chang, WSW;Lin, CC
國家衛生研究院 2009-10 Identification of trypsin-inhibitory site and structure determination of human SPINK2 serine proteinase inhibitor Chen, T;Lee, TR;Liang, WG;Chang, WSW;Lyu, PC
國家衛生研究院 2009-07-23 Generation of ligand-based pharmacophore model and virtual screening for identification of novel tubulin inhibitors with potent anticancer activity Chiang, YK;Kuo, CC;Wu, YS;Chen, CT;Coumar, MS;Wu, JS;Hsieh, HP;Chang, CY;Jseng, HY;Wu, MH;Leou, JS;Song, JS;Chang, JY;Lyu, PC;Chao, YS;Wu, SY
國家衛生研究院 2008-12 Mana-Hox displays anticancer activity against prostate cancer cells through tubulin depolymerization and DNA damage stress Hsiao, CJ;Ho, YF;Hsu, JTA;Chang, WL;Chen, YC;Shen, YC;Lyu, PC;Guh, JH
國家衛生研究院 2008-11-01 Crystal structure of DFA0005 complexed with alpha-ketoglutarate: A novel member of the ICL/PEPM superfamily from alkali-tolerant Deinococcus ficus Liao, CJ;Chin, KH;Lin, CH;Tsai, PSF;Lyu, PC;Young, CC;Wang, AHJ;Chou, SH
國立臺灣大學 2008 WRC-213, an l-methionine-conjugated mitoxantrone derivative, displays anticancer activity with reduced cardiotoxicity and drug resistance: Identification of topoisomerase II inhibition and apoptotic machinery in prostate cancers. Hsiao, CJ; Li, T-K; Chan, YL; Hsin, LW; Liao, CH; Lee, CH; Lyu, PC; Guh, JH.
國家衛生研究院 2006-10-19 Structural basis for the structure-activity relationships of peroxisome proliferator-activated receptor agonists Mahindroo, N; Peng, YH; Lin, CH; Tan, UK; Prakash, E; Lien, TW; Lu, IL; Lee, HJ; Hsu, JTA; Chen, X; Liao, CC; Lyu, PC; Chao, YS; Wu, SY; Hsieh, HP
國家衛生研究院 2006-02-09 Indol-1-yl acetic acids as peroxisome proliferator-activated receptor agonists: Design, synthesis, structural biology, and molecular docking studies Mahindroo, N; Wang, CC; Liao, CC; Huang, CF; Lu, IL; Lien, TW; Peng, YH; Huang, WJ; Lin, YT; Hsu, MC; Lin, CH; Tsai, CH; Hsu, JTA; Chen, X; Lyu, PC; Chao, YS; Wu, SY; Hsieh, HP
臺北醫學大學 2006 Biosynthesis of fluorescent allophycocyanin alpha-subunits by autocatalytic bilin attachment. 闕壯卿; Hu IC; Lee TR; Lin HF; Chiueh CC; Lyu PC;
元培科技大學 2006 Human pancreatitis-associated protein forms fibrillar aggregates with a native-like conformation. Ho MR; Lou YC; Lin WC; Lyu PC; Huang WN; Chen C.

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