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Institution	Date	Title	Author
臺北醫學大學	2011	Synthesis and biological evaluation of 1-(40-Indolyl and 60-Quinolinyl) indoles as a new class of potent anticancer agents.	Lai, MJ;Chang, JY;Lee, HY;Kuo, CC;Lin, MH;Hsieh, HP;Chang, CY;Wu, JS;Wu, SY;Shey;KS;Liou, JP
國家衛生研究院	2010-12	Discovery of non-glycoside sodium-dependent glucose Co-transporter 2 (SGLT2) inhibitors by ligand-based virtual screening	Wu, JS;Peng, YH;Wu, JM;Hsieh, CJ;Wu, SH;Coumar, MS;Song, JS;Lee, JC;Tsai, CH;Chen, CT;Liu, YW;Chao, YS;Wu, SY
國家衛生研究院	2010-10-06	吡咯烷化合物	Jiaang, WT;Chen, X;Wu, SY;Hsieh, HP;Chao, YS
國家衛生研究院	2010-10	Structural basis for the improved potency of peroxisome proliferator-activated receptor (PPAR) agonists	Peng, YH;Coumar, MS;Leou, JS;Wu, JS;Shiao, HY;Lin, CH;Lin, WH;Lien, TW;Chen, X;Hsu, JT;Chao, YS;Huang, CF;Lyu, PC;Hsieh, HP;Wu, SY
國家衛生研究院	2010-09	Endogenous latent membrane protein 1 in Epstein-Barr virus-infected nasopharyngeal carcinoma cells attracts T lymphocytes through upregulation of multiple chemokines	Lai, HC;Hsiao, JR;Chen, CW;Wu, SY;Lee, CH;Su, IJ;Takada, K;Chang, Y
國家衛生研究院	2010-09	Cancer cells acquire mitotic drug resistance properties through beta i-tubulin mutations and alterations in the expression of beta-tubulin isotypes	Cheung, CHA;Wu, SY;Lee, TR;Chang, CY;Wu, JS;Hsieh, HP;Chang, JY
美和科技大學	2010-09	Increasing hybridoma viability and antibody repertoire after the cell fusion by the use of human plasma as an alternative supplement	Lee RJ;Wu JS;Juang RH;Wu YJ;Lin CY;Wu SY;Huang PR;Chu CH;Chin LT;Chen HM
國家衛生研究院	2010-08	Lead optimization of furanopyrimidine Aurora kinase inhibitors: Development of in vivo active agents in tumor xenograft models	Hsieh, HP;Chu, CY;Coumar, MS;Lin, WH;Chen, CT;Hsu, TA;Wu, SY;Chao, YS
國家衛生研究院	2010-06-15	Fast-forwarding hit to lead: Aurora and epidermal growth factor receptor kinase inhibitor lead identification	Coumar, MS;Chu, CY;Lin, CW;Shiao, HY;Ho, YL;Reddy, R;Lin, WH;Chen, CH;Peng, YH;Leou, JS;Lien, TW;Huang, CT;Fang, MY;Wu, SH;Wu, JS;Chittimalla, SK;Song, JS;Hsu, JT;Wu, SY;Liao, CC;Chao, YS;Hsieh, HP
國家衛生研究院	2010-03-30	Pyrrolidine compounds	Jiaang, WT;Chen, X;Wu, SY;Chao, YS;Hsieh, HP
國家衛生研究院	2010-03-11	5-Amino-2-Aroylquinolines as Highly Potent Tubulin Polymerization Inhibitors	Nien, CY;Chen, YC;Kuo, CC;Hsieh, HP;Chang, CY;Wu, JS;Wu, SY;Liou, JP;Chang, JY
國家衛生研究院	2010-02-01	Identification, SAR studies, and X-ray Co-crystallographic analysis of a novel furanopyrimidine aurora kinase a inhibitor	Coumar, MS;Tsai, MT;Chu, CY;Uang, BJ;Lin, WH;Chang, CY;Chang, TY;Leou, JS;Teng, CH;Wu, JS;Fang, MY;Chen, CH;Hsu, JTA;Wu, SY;Chao, YS;Hsieh, HP
國立聯合大學	2010	Optimizing coagulant demand by Nephelometric Turbidimeter Monitoring System (NTMS)	Cheng, WP; Yu, RF; Hsieh, YJ; Wu, SY; Huang, YW; Chen, SM
臺北醫學大學	2010	5-Amino-2-Aroylquinolines as Highly Potent Tubulin Polymerization Inhibitors	Nien, CY;Chen, YC;Kuo, CC;Hsieh, HP;Chang, CY;Wu, JS;Wu, SY;Liou, JP;Chang, JY
國家衛生研究院	2009-10	(1,3-Diphenyl-1H-pyrazol-4-yl)-methylamine analogues as inhibitors of dipeptidyl peptidases	Hsu, T;Chen, CT;Tsai, TY;Cheng, JH;Wu, SY;Chang, CN;Chien, CH;Yeh, KC;Huang, YW;Huang, CL;Huang, CY;Wu, SH;Chiang, YK;Wang, MH;Chao, YS;Chen, X;Jiaang, WT
國家衛生研究院	2009-08-13	Synthesis and evaluation of 3-aroylindoles as anticancer agents: Metabolite approach	Wu, YS;Coumar, MS;Chang, JY;Sun, HY;Kuo, FM;Kuo, CC;Chen, YJ;Chang, CY;Hsiao, CL;Liou, JP;Chen, CP;Yao, HT;Chiang, YK;Tan, UK;Chen, CT;Chu, CY;Wu, SY;Yeh, TK;Lin, CY;Hsieh, HP
中國醫藥大學	2009-08	Synthesis and Evaluation of 3-Aroylindoles as Anticancer Agents: Metabolite Approach.	(Wu YS); (Coumar MS); (Chang JY); (Sun HY); (Kuo FM); (Kuo CC); (Chen YJ); (Chang CY); (Hsiao CL); (Liou JP); (Chen CP); 姚賢宗(Hsien-Tsung Yao); (Chiang YK); (Tan UK); (Chen CT); (Chu CY); (Wu SY); (Yeh TK); (Lin CY); (Hsieh HP)*
國家衛生研究院	2009-07-23	Generation of ligand-based pharmacophore model and virtual screening for identification of novel tubulin inhibitors with potent anticancer activity	Chiang, YK;Kuo, CC;Wu, YS;Chen, CT;Coumar, MS;Wu, JS;Hsieh, HP;Chang, CY;Jseng, HY;Wu, MH;Leou, JS;Song, JS;Chang, JY;Lyu, PC;Chao, YS;Wu, SY
國家衛生研究院	2009-06	A three-dimensional pharmacophore model for dipeptidyl peptidase IV inhibitiors [Erratum: European Journal of Medicinal Chemistry. 2008 Aug;43(8):1603-1611.]	Lu, IL;Tsai, KC;Chiang, YK;Jiaang, WT;Wu, SH;Mahindroo, N;Chien, CH;Lee, SJ;Chen, X;Chao, YS;Wu, SY
國家衛生研究院	2009-05-15	Endoplasmic reticulum stress triggers XBP-1-mediated up-regulation of an EBV oncoprotein in nasopharyngeal carcinoma	Hsiao, JR;Chang, KC;Chen, CW;Wu, SY;Su, IJ;Hsu, MC;Jin, YT;Tsai, ST;Takada, K;Chang, Y
國家衛生研究院	2009-04-23	Design and structural analysis of novel pharmacophores for potent and selective peroxisome proliferator-activated receptor gamma agonists	Lin, CH;Peng, YH;Coumar, MS;Chittimalla, SK;Liao, CC;Lyn, PC;Huang, CC;Lien, TW;Lin, WH;Hsu, JT;Cheng, JH;Chen, X;Wu, JS;Chao, YS;Lee, HJ;Juo, CG;Wu, SY;Hsieh, HP
國家衛生研究院	2009-03	Discovery and development of novel furano-pyrimidine analogs as Aurora kinase inhibitors	Hsieh, HP;Coumar, MS;Lin, CW;Reddy, GR;Tsai, MT;Lin, WH;Hsu, TA;Wu, SY
國家衛生研究院	2009-02-26	Structure-based drug design of novel aurora kinase a inhibitors: Structural basis for potency and specificity	Coumar, MS;Leou, JS;Shukla, P;Wu, JS;Dixit, AK;Lin, WH;Chang, CY;Lien, TW;Tan, UK;Chen, CH;Hsu, JTA;Chao, YS;Wu, SY;Hsieh, HP
國家衛生研究院	2009-01-22	Pyrrolidine compounds	Chao, YS;Chen, X;Hsieh, HP;Jiaang, WT;Wu, SY
國立臺灣大學	2009-01	Effect of benazepril on systemic blood pressure in small breed dogs with chronic degenerative valvular diseases.	Wu, SY; Huang, HP
國家衛生研究院	2008-12-25	Synthesis and structure-activity relationships of 2-amino-1-aroylnaphthalene and 2-hydroxy-1-aroylnaphthalenes as potent antitubulin agents	Reddy, GR;Kuo, CC;Tan, UK;Coumar, MS;Chang, CY;Chiang, YK;Lai, MJ;Yeh, JY;Wu, SY;Chang, JY;Liou, JP;Hsieh, HP
國立臺灣大學	2008-11	YC-1 induces apoptosis of human renal carcinoma A498 cells in vitro and in vivo through activation of the JNK pathway.	Wu, SY; Pan, SL; Chen, TH; Liao, CH; Huang, DY; Guh, JH; Chang, YL; Kuo, SC; Lee, FY; Teng, CM.
國家衛生研究院	2008-08	A three-dimensional pharmacophore model for dipeptidyl peptidase IV inhibitors	Lu, IL;Tsai, KC;Chiang, YK;Jiaang, WT;Wu, SH;Mahindroo, N;Chien, CH;Lee, SJ;Chen, X;Chao, YS;Wu, SY
國家衛生研究院	2008-07-21	吡咯啉啶化合物	Jiaang, WT;Wu, SY;Chen, X;Chao, YS;Hsieh, HP
國家衛生研究院	2008-07-01	Pyrrolidine compounds	Jiaang, WT;Chen, X;Wu, SY;Hsieh, HP;Chao, YS
國家衛生研究院	2008-04	Epstein-Barr virus lytic transactivator Zta enhances chemotactic activity through induction of interleukin-8 in nasopharyngeal carcinoma cells	Hsu, M; Wu, SY; Chang, SS; Su, IJ; Tsai, CH; Lai, SJ; Shiau, AL; Takada, K; Chang, Y
國家衛生研究院	2008-03-01	Aurora kinase A inhibitors: Identification, SAR exploration and molecular modeling of 6,7-dihydro-4H-pyrazolo-[1,5-a]pyrrolo[3,4-d]pyrimidine-5,8-dione scaffold	Coumar, MS; Wu, JS; Leou, JS; Tan, UK; Chang, CY; Chang, TY; Lin, WH; Hsu, JTA; Chao, YS; Wu, SY; Hsieh, HP
國家衛生研究院	2008	Structure-based inhibitors exhibit differential activities against Helicobacter pylori and Escherichia coli undecaprenyl pyrophosphate synthases	Kuo, CJ; Guo, RT; Lu, IL; Liu, HG; Wu, SY; Ko, TP; Wang, AHJ; Liang, PH
臺北醫學大學	2008	Synthesis and Structure-Activity Relationships of 2-Amino and 2-Hydroxy-1-Aroylnaphthalenes as Potent Antitubulin Agents	劉景平; Reddy GR; Kuo CC; Tan UK; Coumar MS; Chang CY; Lai MJ; Wu SY; Chang JY; Liou JP; Hsieh HP
臺北醫學大學	2008	Domain and Functional Analysis of a Novel Platelet-Endothelial Cell Surface Protein; SCUBE1.	鄭建睿; Tu CF; Yan YT; Wu SY; Djoko B; Tsai MT; Cheng CJ; Yang RB
國立臺灣大學	2008	Epstein-Barr virus lytic transactivator Zta enhances chemotactic activity through induction of interleukin-8 in nasopharyngeal carcinoma cells.	Hsu, M; Wu, SY; Chang, SS; Su, IJ; Tsai, CH; Lai, SJ; Shiau, AL; Takada, K; Chang, Y
國家衛生研究院	2007	Crystal structures and computer screened inhibitors of Helicobacter pylori undecaprenyl pyrophosphate synthase	Kuo, CJ;Guo, RT;Lu, IL;Liu, HG;Wu, SY;Ko, TP;Wang, AHJ;Liang, PH
臺北醫學大學	2007	Menthol inhibits WEHI-3 leukemia cells in vitro and in vivo	楊沂淵; Lu HF; Liu JY; Hsueh SC; Yang YY; Yang JS; Tan TW; Kok LF; Lu CC; Lan SH; Wu SY; et al.;
國家衛生研究院	2006-10-19	Structural basis for the structure-activity relationships of peroxisome proliferator-activated receptor agonists	Mahindroo, N; Peng, YH; Lin, CH; Tan, UK; Prakash, E; Lien, TW; Lu, IL; Lee, HJ; Hsu, JTA; Chen, X; Liao, CC; Lyu, PC; Chao, YS; Wu, SY; Hsieh, HP
國家衛生研究院	2006-08-24	Structure-based drug design and structural biology study of novel nonpeptide inhibitors of severe acute respiratory syndrome coronavirus main protease	Lu, IL; Mahindroo, N; Liang, PH; Peng, YH; Kuo, CJ; Tsai, KC; Hsieh, HP; Chao, YS; Wu, SY
國家衛生研究院	2006-08	Induction of the early growth response 1 gene by Epstein-Barr virus lytic transactivator Zta	Chang, Y; Lee, HH; Chen, YT; Lu, J; Wu, SY; Chen, CW; Takada, K; Tsai, CH
國家衛生研究院	2006-06-15	Discovery of a novel family of SARS-CoV protease inhibitors by virtual screening and 3D-QSAR studies	Tsai, KC; Chen, SY; Liang, PH; Lu, IL; Mahindroo, N; Hsieh, HP; Chao, YS; Liu, L; Liu, D; Lien, W; Lin, TH; Wu, SY
國家衛生研究院	2006-05-04	Structure-based drug design of a novel family of PPAR gamma partial agonists: Virtual screening, X-ray crystallography, and in vitro/in vivo biological activities	Lu, IL; Huang, CF; Peng, YH; Lin, YT; Hsieh, HP; Chen, CT; Lien, TW; Lee, HJ; Mahindroo, N; Prakash, E; Yueh, A; Chen, HY; Goparaju, CMV; Chen, X; Liao, CC; Chao, YS; Hsu, JTA; Wu, SY
國家衛生研究院	2006-02-09	Indol-1-yl acetic acids as peroxisome proliferator-activated receptor agonists: Design, synthesis, structural biology, and molecular docking studies	Mahindroo, N; Wang, CC; Liao, CC; Huang, CF; Lu, IL; Lien, TW; Peng, YH; Huang, WJ; Lin, YT; Hsu, MC; Lin, CH; Tsai, CH; Hsu, JTA; Chen, X; Lyu, PC; Chao, YS; Wu, SY; Hsieh, HP
國家衛生研究院	2006-01-12	2-[3-[2-[(2S)-2-cyano-1-pyrrolidinyl]-2-oxoethylamino]-3-methyl-1-oxobutyl]-1,2,3,4-tetrahydroisoquinoline: A potent, selective, and orally bioavailable dipeptide-derived inhibitor of dipeptidyl peptidase IV	Tsu, H; Chen, X; Chen, CT; Lee, SJ; Chang, CN; Kao, KH; Coumar, MS; Yeh, YT; Chien, CH; Wang, HS; Lin, KT; Chang, YY; Wu, SH; Chen, YS; Lu, IL; Wu, SY; Tsai, TY; Chen, WC; Hsieh, HP; Chao, YS; Jiaang, WT
國立臺灣大學	2006-01	Population ecology of the southeastern Asian house mouse (Musmusculus castaneus) inhabiting rice granaries in Taiwan.	Wu, SY; Lin, YTK; Yu, HT
國立臺灣大學	2006-01	Population ecology of house mouse (Mus musculus castaneus) inhabiting rice granaries in Taiwan.	Wu, SY; Lin, YK; Yu, HT
國立臺灣大學	2006	Induction of the early growth response 1 gene by Epstein-Barr virus lytic transactivator Zta.	Chang, Y; Lee, HH; Chen, YT; Lu, J; Wu, SY; Chen, CW; Takada, K; Tsai, CH
國家衛生研究院	2005-12-29	Novel indole-based peroxisome proliferator-activated receptor agonists: Design, SAR, structural biology, and biological activities	Mahindroo, N; Huang, CF; Peng, YH; Wang, CC; Liao, CC; Lien, TW; Chittimalla, SK; Huang, WJ; Chai, CH; Prakash, E; Chen, CP; Hsu, TA; Peng, CH; Lu, IL; Lee, LH; Chang, YW; Chen, WC; Chou, YC; Chen, CT; Goparaju, CMV; Chen, YS; Lan, SJ; Yu, MC; Chen, X; Chao, YS; Wu, SY; Hsieh, HP
國家衛生研究院	2005-12-15	The effect of N-terminal truncation on double-dimer assembly of goose delta-crystallin	Lee, HJ; Lai, YH; Wu, SY; Chen, YH

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