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机构 日期 题名 作者
國家衛生研究院 2012-05 The HPV E6 oncoprotein targets histone methyltransferases for modulating specific gene transcription Hsu, CH;Peng, KL;Jhang, HC;Lin, CH;Wu, SY;Chiang, CM;Lee, SC;Yu, WCY;Juan, LJ
國家衛生研究院 2012-03-20 Fused bicyclic pyrimidine compounds as aurora kinase inhibitors Hsieh, HP;Coumar, MS;Hsu, TA;Wu, SY;Chao, YS
國家衛生研究院 2012-02 Discovery of novel stem cell mobilizers that target the CXCR4 receptor Wu, CH;Chang, CP;Song, JS;Jan, JJ;Chou, MC;Wu, SH;Yeh, KC;Wong, YC;Hsieh, CJ;Chen, CT;Kao, TT;Wu, SY;Yeh, CF;Tseng, CT;Chao, YS;Shia, KS
國家衛生研究院 2012-01-17 Pyrrolidine compounds Jiaang, WT;Chen, X;Wu, SY;Hsieh, HP;Chao, YS
國立成功大學 2011-12 Ras-Related Tumorigenesis Is Suppressed by BNIP3-Mediated Autophagy through Inhibition of Cell Proliferation Wu, SY; Lan, SH; Cheng, DE; Chen, WK; Shen, CH; Lee, YR; Zuchini, R; Liu, HS
國家衛生研究院 2011-11 Immunization with apoptotic phagocytes containing histoplasma capsulatum activates functional CD8(+) T cells to protect against histoplasmosis Hsieh, SH;Lin, JS;Huang, JH;Wu, SY;Chu, CL;Kung, JT;Wu-Hsieh, BA
國家衛生研究院 2011-09 Synthesis and biological evaluation of 1-(4′-Indolyl and 6′-Quinolinyl) indoles as a new class of potent anticancer agents Lai, MJ;Chang, JY;Lee, HY;Kuo, CC;Lin, MH;Hsieh, HP;Chang, CY;Wu, JS;Wu, SY;Shey, KS;Liou, JP
國家衛生研究院 2011-07 Epstein-Barr virus Zta-Induced immunomodulators from nasopharyngeal carcinoma cells upregulate interleukin-10 production from monocytes Lee, CH;Yeh, TH;Lai, HC;Wu, SY;Su, IJ;Takada, K;Chang, Y
國家衛生研究院 2011-04-28 Scaffold-hopping strategy: Synthesis and biological evaluation of 5,6-Fused bicyclic heteroaromatics to identify orally bioavailable anticancer agents Tung, YS;Coumar, MS;Wu, YS;Shiao, HY;Chang, JY;Liou, JP;Shukla, P;Chang, CW;Chang, CY;Kuo, CC;Yeh, TK;Lin, CY;Wu, JS;Wu, SY;Liao, CC;Hsieh, HP
臺北醫學大學 2011 Synthesis and Biological Evaluation of 1-(4’-Indolyl and 6’-Quinolinyl)indoles as a New Class of Potent Anticancer Agents Lia, MJ;Chang, JY;Lee, HY;Kuo, CC;Lin, MH;Hsieh, HP;Chang, CY;Wu, JS;Wu, SY;Shey, KS;Liou, JP
臺北醫學大學 2011 Synthesis and biological evaluation of 1-(40-Indolyl and 60-Quinolinyl) indoles as a new class of potent anticancer agents. Lai, MJ;Chang, JY;Lee, HY;Kuo, CC;Lin, MH;Hsieh, HP;Chang, CY;Wu, JS;Wu, SY;Shey;KS;Liou, JP
國家衛生研究院 2010-12 Discovery of non-glycoside sodium-dependent glucose Co-transporter 2 (SGLT2) inhibitors by ligand-based virtual screening Wu, JS;Peng, YH;Wu, JM;Hsieh, CJ;Wu, SH;Coumar, MS;Song, JS;Lee, JC;Tsai, CH;Chen, CT;Liu, YW;Chao, YS;Wu, SY
國家衛生研究院 2010-10-06 吡咯烷化合物 Jiaang, WT;Chen, X;Wu, SY;Hsieh, HP;Chao, YS
國家衛生研究院 2010-10 Structural basis for the improved potency of peroxisome proliferator-activated receptor (PPAR) agonists Peng, YH;Coumar, MS;Leou, JS;Wu, JS;Shiao, HY;Lin, CH;Lin, WH;Lien, TW;Chen, X;Hsu, JT;Chao, YS;Huang, CF;Lyu, PC;Hsieh, HP;Wu, SY
國家衛生研究院 2010-09 Endogenous latent membrane protein 1 in Epstein-Barr virus-infected nasopharyngeal carcinoma cells attracts T lymphocytes through upregulation of multiple chemokines Lai, HC;Hsiao, JR;Chen, CW;Wu, SY;Lee, CH;Su, IJ;Takada, K;Chang, Y
國家衛生研究院 2010-09 Cancer cells acquire mitotic drug resistance properties through beta i-tubulin mutations and alterations in the expression of beta-tubulin isotypes Cheung, CHA;Wu, SY;Lee, TR;Chang, CY;Wu, JS;Hsieh, HP;Chang, JY
美和科技大學 2010-09 Increasing hybridoma viability and antibody repertoire after the cell fusion by the use of human plasma as an alternative supplement Lee RJ;Wu JS;Juang RH;Wu YJ;Lin CY;Wu SY;Huang PR;Chu CH;Chin LT;Chen HM
國家衛生研究院 2010-08 Lead optimization of furanopyrimidine Aurora kinase inhibitors: Development of in vivo active agents in tumor xenograft models Hsieh, HP;Chu, CY;Coumar, MS;Lin, WH;Chen, CT;Hsu, TA;Wu, SY;Chao, YS
國家衛生研究院 2010-06-15 Fast-forwarding hit to lead: Aurora and epidermal growth factor receptor kinase inhibitor lead identification Coumar, MS;Chu, CY;Lin, CW;Shiao, HY;Ho, YL;Reddy, R;Lin, WH;Chen, CH;Peng, YH;Leou, JS;Lien, TW;Huang, CT;Fang, MY;Wu, SH;Wu, JS;Chittimalla, SK;Song, JS;Hsu, JT;Wu, SY;Liao, CC;Chao, YS;Hsieh, HP
國家衛生研究院 2010-03-30 Pyrrolidine compounds Jiaang, WT;Chen, X;Wu, SY;Chao, YS;Hsieh, HP
國家衛生研究院 2010-03-11 5-Amino-2-Aroylquinolines as Highly Potent Tubulin Polymerization Inhibitors Nien, CY;Chen, YC;Kuo, CC;Hsieh, HP;Chang, CY;Wu, JS;Wu, SY;Liou, JP;Chang, JY
國家衛生研究院 2010-02-01 Identification, SAR studies, and X-ray Co-crystallographic analysis of a novel furanopyrimidine aurora kinase a inhibitor Coumar, MS;Tsai, MT;Chu, CY;Uang, BJ;Lin, WH;Chang, CY;Chang, TY;Leou, JS;Teng, CH;Wu, JS;Fang, MY;Chen, CH;Hsu, JTA;Wu, SY;Chao, YS;Hsieh, HP
國立聯合大學 2010 Optimizing coagulant demand by Nephelometric Turbidimeter Monitoring System (NTMS) Cheng, WP; Yu, RF; Hsieh, YJ; Wu, SY; Huang, YW; Chen, SM
臺北醫學大學 2010 5-Amino-2-Aroylquinolines as Highly Potent Tubulin Polymerization Inhibitors Nien, CY;Chen, YC;Kuo, CC;Hsieh, HP;Chang, CY;Wu, JS;Wu, SY;Liou, JP;Chang, JY
國家衛生研究院 2009-10 (1,3-Diphenyl-1H-pyrazol-4-yl)-methylamine analogues as inhibitors of dipeptidyl peptidases Hsu, T;Chen, CT;Tsai, TY;Cheng, JH;Wu, SY;Chang, CN;Chien, CH;Yeh, KC;Huang, YW;Huang, CL;Huang, CY;Wu, SH;Chiang, YK;Wang, MH;Chao, YS;Chen, X;Jiaang, WT
國家衛生研究院 2009-08-13 Synthesis and evaluation of 3-aroylindoles as anticancer agents: Metabolite approach Wu, YS;Coumar, MS;Chang, JY;Sun, HY;Kuo, FM;Kuo, CC;Chen, YJ;Chang, CY;Hsiao, CL;Liou, JP;Chen, CP;Yao, HT;Chiang, YK;Tan, UK;Chen, CT;Chu, CY;Wu, SY;Yeh, TK;Lin, CY;Hsieh, HP
中國醫藥大學 2009-08 Synthesis and Evaluation of 3-Aroylindoles as Anticancer Agents: Metabolite Approach. (Wu YS); (Coumar MS); (Chang JY); (Sun HY); (Kuo FM); (Kuo CC); (Chen YJ); (Chang CY); (Hsiao CL); (Liou JP); (Chen CP); 姚賢宗(Hsien-Tsung Yao); (Chiang YK); (Tan UK); (Chen CT); (Chu CY); (Wu SY); (Yeh TK); (Lin CY); (Hsieh HP)*
國家衛生研究院 2009-07-23 Generation of ligand-based pharmacophore model and virtual screening for identification of novel tubulin inhibitors with potent anticancer activity Chiang, YK;Kuo, CC;Wu, YS;Chen, CT;Coumar, MS;Wu, JS;Hsieh, HP;Chang, CY;Jseng, HY;Wu, MH;Leou, JS;Song, JS;Chang, JY;Lyu, PC;Chao, YS;Wu, SY
國家衛生研究院 2009-06 A three-dimensional pharmacophore model for dipeptidyl peptidase IV inhibitiors [Erratum: European Journal of Medicinal Chemistry. 2008 Aug;43(8):1603-1611.] Lu, IL;Tsai, KC;Chiang, YK;Jiaang, WT;Wu, SH;Mahindroo, N;Chien, CH;Lee, SJ;Chen, X;Chao, YS;Wu, SY
國家衛生研究院 2009-05-15 Endoplasmic reticulum stress triggers XBP-1-mediated up-regulation of an EBV oncoprotein in nasopharyngeal carcinoma Hsiao, JR;Chang, KC;Chen, CW;Wu, SY;Su, IJ;Hsu, MC;Jin, YT;Tsai, ST;Takada, K;Chang, Y
國家衛生研究院 2009-04-23 Design and structural analysis of novel pharmacophores for potent and selective peroxisome proliferator-activated receptor gamma agonists Lin, CH;Peng, YH;Coumar, MS;Chittimalla, SK;Liao, CC;Lyn, PC;Huang, CC;Lien, TW;Lin, WH;Hsu, JT;Cheng, JH;Chen, X;Wu, JS;Chao, YS;Lee, HJ;Juo, CG;Wu, SY;Hsieh, HP
國家衛生研究院 2009-03 Discovery and development of novel furano-pyrimidine analogs as Aurora kinase inhibitors Hsieh, HP;Coumar, MS;Lin, CW;Reddy, GR;Tsai, MT;Lin, WH;Hsu, TA;Wu, SY
國家衛生研究院 2009-02-26 Structure-based drug design of novel aurora kinase a inhibitors: Structural basis for potency and specificity Coumar, MS;Leou, JS;Shukla, P;Wu, JS;Dixit, AK;Lin, WH;Chang, CY;Lien, TW;Tan, UK;Chen, CH;Hsu, JTA;Chao, YS;Wu, SY;Hsieh, HP
國家衛生研究院 2009-01-22 Pyrrolidine compounds Chao, YS;Chen, X;Hsieh, HP;Jiaang, WT;Wu, SY
國立臺灣大學 2009-01 Effect of benazepril on systemic blood pressure in small breed dogs with chronic degenerative valvular diseases. Wu, SY; Huang, HP
國家衛生研究院 2008-12-25 Synthesis and structure-activity relationships of 2-amino-1-aroylnaphthalene and 2-hydroxy-1-aroylnaphthalenes as potent antitubulin agents Reddy, GR;Kuo, CC;Tan, UK;Coumar, MS;Chang, CY;Chiang, YK;Lai, MJ;Yeh, JY;Wu, SY;Chang, JY;Liou, JP;Hsieh, HP
國立臺灣大學 2008-11 YC-1 induces apoptosis of human renal carcinoma A498 cells in vitro and in vivo through activation of the JNK pathway. Wu, SY; Pan, SL; Chen, TH; Liao, CH; Huang, DY; Guh, JH; Chang, YL; Kuo, SC; Lee, FY; Teng, CM.
國家衛生研究院 2008-08 A three-dimensional pharmacophore model for dipeptidyl peptidase IV inhibitors Lu, IL;Tsai, KC;Chiang, YK;Jiaang, WT;Wu, SH;Mahindroo, N;Chien, CH;Lee, SJ;Chen, X;Chao, YS;Wu, SY
國家衛生研究院 2008-07-21 吡咯啉啶化合物 Jiaang, WT;Wu, SY;Chen, X;Chao, YS;Hsieh, HP
國家衛生研究院 2008-07-01 Pyrrolidine compounds Jiaang, WT;Chen, X;Wu, SY;Hsieh, HP;Chao, YS
國家衛生研究院 2008-04 Epstein-Barr virus lytic transactivator Zta enhances chemotactic activity through induction of interleukin-8 in nasopharyngeal carcinoma cells Hsu, M; Wu, SY; Chang, SS; Su, IJ; Tsai, CH; Lai, SJ; Shiau, AL; Takada, K; Chang, Y
國家衛生研究院 2008-03-01 Aurora kinase A inhibitors: Identification, SAR exploration and molecular modeling of 6,7-dihydro-4H-pyrazolo-[1,5-a]pyrrolo[3,4-d]pyrimidine-5,8-dione scaffold Coumar, MS; Wu, JS; Leou, JS; Tan, UK; Chang, CY; Chang, TY; Lin, WH; Hsu, JTA; Chao, YS; Wu, SY; Hsieh, HP
國家衛生研究院 2008 Structure-based inhibitors exhibit differential activities against Helicobacter pylori and Escherichia coli undecaprenyl pyrophosphate synthases Kuo, CJ; Guo, RT; Lu, IL; Liu, HG; Wu, SY; Ko, TP; Wang, AHJ; Liang, PH
臺北醫學大學 2008 Synthesis and Structure-Activity Relationships of 2-Amino and 2-Hydroxy-1-Aroylnaphthalenes as Potent Antitubulin Agents 劉景平; Reddy GR; Kuo CC; Tan UK; Coumar MS; Chang CY; Lai MJ; Wu SY; Chang JY; Liou JP; Hsieh HP
臺北醫學大學 2008 Domain and Functional Analysis of a Novel Platelet-Endothelial Cell Surface Protein; SCUBE1. 鄭建睿; Tu CF; Yan YT; Wu SY; Djoko B; Tsai MT; Cheng CJ; Yang RB
國立臺灣大學 2008 Epstein-Barr virus lytic transactivator Zta enhances chemotactic activity through induction of interleukin-8 in nasopharyngeal carcinoma cells. Hsu, M; Wu, SY; Chang, SS; Su, IJ; Tsai, CH; Lai, SJ; Shiau, AL; Takada, K; Chang, Y
國家衛生研究院 2007 Crystal structures and computer screened inhibitors of Helicobacter pylori undecaprenyl pyrophosphate synthase Kuo, CJ;Guo, RT;Lu, IL;Liu, HG;Wu, SY;Ko, TP;Wang, AHJ;Liang, PH
臺北醫學大學 2007 Menthol inhibits WEHI-3 leukemia cells in vitro and in vivo 楊沂淵; Lu HF; Liu JY; Hsueh SC; Yang YY; Yang JS; Tan TW; Kok LF; Lu CC; Lan SH; Wu SY; et al.;
國家衛生研究院 2006-10-19 Structural basis for the structure-activity relationships of peroxisome proliferator-activated receptor agonists Mahindroo, N; Peng, YH; Lin, CH; Tan, UK; Prakash, E; Lien, TW; Lu, IL; Lee, HJ; Hsu, JTA; Chen, X; Liao, CC; Lyu, PC; Chao, YS; Wu, SY; Hsieh, HP
國家衛生研究院 2006-08-24 Structure-based drug design and structural biology study of novel nonpeptide inhibitors of severe acute respiratory syndrome coronavirus main protease Lu, IL; Mahindroo, N; Liang, PH; Peng, YH; Kuo, CJ; Tsai, KC; Hsieh, HP; Chao, YS; Wu, SY

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