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Institution	Date	Title	Author
國家衛生研究院	2013-02	Epstein-Barr virus Zta upregulates matrix metalloproteinases 3 and 9 that synergistically promote cell invasion in vitro	Lan, YY;Yeh, TH;Lin, WH;Wu, SY;Lai, HC;Chang, FH;Takada, K;Chang, Y
臺北醫學大學	2013	MicroRNA-17-5p Post-transcriptionally Regulates p21 Expression in Irradiated Betel Quid Chewing-Related Oral Squamous Cell Carcinoma Cells	Wu, SY;Lin, KC;Chiou, JF;Jeng, SC;Cheng, WH;Chang, CI;Lin, WC;Wu, LL;Lee, HL;Chen, RJ
臺北醫學大學	2013	MicroRNA-17-5p post-transcriptionally regulates p21 expression in irradiated betel quid chewing-related oral squamous cell carcinomas cells	Wu, SY;Lin, KC;Chiou, JF;Jeng, SC;Cheng, WH;Chang, CL;Lin, WC;Wu, LL;Lee, HL;Chen, RJ.
臺北醫學大學	2013	Pharmacological closure of patent ductus arteriosus in extreme low birth weight infants: A comparison of the efficacy and side effects between indomethacin and ibuprofen	Chen, CM;Florens, A;Wu, SY;Yeh, TF
臺北醫學大學	2013	Furanylazaindoles: Potent Anticancer Agents in Vitro and in Vivo	Lee, HY;Pan, SL;Su, MC;Liu, YM;Kuo, CC;Chang, YT;Wu, JS;Nien, CY;Mehndiratta, S;Chang, CY;Wu, SY;Lai, MJ;JY, Chang;JP, Liou
國家衛生研究院	2012-08	Development of an anti-influenza drug screening assay targeting nucleoproteins with tryptophan fluorescence quenching	Hung, HC;Liu, CL;Hsu, JT;Horng, JT;Fang, MY;Wu, SY;Ueng, SH;Wang, MY;Yaw, CW;Hou, MH
國家衛生研究院	2012-07	Physalin F induces cell apoptosis in human renal carcinoma cells by targeting NF-kappaB and generating reactive oxygen species	Wu, SY;Leu, YL;Chang, YL;Wu, TS;Kuo, PC;Liao, YR;Teng, CM;Pan, SL
國家衛生研究院	2012-06	Epstein-Barr virus latent membrane protein 2A promotes invasion of nasopharyngeal carcinoma cells through ERK/Fra-1-mediated induction of matrix metalloproteinase 9	Lan, YY;Hsiao, JR;Chang, KC;Chang, JSM;Chen, CW;Lai, HC;Wu, SY;Yeh, TH;Chang, FH;Lin, WH;Su, IJ;Chang, Y
國家衛生研究院	2012-06	Involvement of transcriptional regulator Ndt80 in stress responses of Candida albicans	Yang, YL;Wu, SY;Hsiung, CA;Chen, CT;Hsiao, CD;Lo, HJ
國家衛生研究院	2012-05-11	作為極光激酶抑制劑之稠合雙環嘧啶化合物	Hsieh, HP;Coumar, MS;Hsu, TA;Wu, SY;Chao, YS
國家衛生研究院	2012-05	The HPV E6 oncoprotein targets histone methyltransferases for modulating specific gene transcription	Hsu, CH;Peng, KL;Jhang, HC;Lin, CH;Wu, SY;Chiang, CM;Lee, SC;Yu, WCY;Juan, LJ
國家衛生研究院	2012-03-20	Fused bicyclic pyrimidine compounds as aurora kinase inhibitors	Hsieh, HP;Coumar, MS;Hsu, TA;Wu, SY;Chao, YS
國家衛生研究院	2012-02	Discovery of novel stem cell mobilizers that target the CXCR4 receptor	Wu, CH;Chang, CP;Song, JS;Jan, JJ;Chou, MC;Wu, SH;Yeh, KC;Wong, YC;Hsieh, CJ;Chen, CT;Kao, TT;Wu, SY;Yeh, CF;Tseng, CT;Chao, YS;Shia, KS
國家衛生研究院	2012-01-17	Pyrrolidine compounds	Jiaang, WT;Chen, X;Wu, SY;Hsieh, HP;Chao, YS
國立成功大學	2011-12	Ras-Related Tumorigenesis Is Suppressed by BNIP3-Mediated Autophagy through Inhibition of Cell Proliferation	Wu, SY; Lan, SH; Cheng, DE; Chen, WK; Shen, CH; Lee, YR; Zuchini, R; Liu, HS
國家衛生研究院	2011-11	Immunization with apoptotic phagocytes containing histoplasma capsulatum activates functional CD8(+) T cells to protect against histoplasmosis	Hsieh, SH;Lin, JS;Huang, JH;Wu, SY;Chu, CL;Kung, JT;Wu-Hsieh, BA
國家衛生研究院	2011-09	Synthesis and biological evaluation of 1-(4′-Indolyl and 6′-Quinolinyl) indoles as a new class of potent anticancer agents	Lai, MJ;Chang, JY;Lee, HY;Kuo, CC;Lin, MH;Hsieh, HP;Chang, CY;Wu, JS;Wu, SY;Shey, KS;Liou, JP
國家衛生研究院	2011-07	Epstein-Barr virus Zta-Induced immunomodulators from nasopharyngeal carcinoma cells upregulate interleukin-10 production from monocytes	Lee, CH;Yeh, TH;Lai, HC;Wu, SY;Su, IJ;Takada, K;Chang, Y
國家衛生研究院	2011-04-28	Scaffold-hopping strategy: Synthesis and biological evaluation of 5,6-Fused bicyclic heteroaromatics to identify orally bioavailable anticancer agents	Tung, YS;Coumar, MS;Wu, YS;Shiao, HY;Chang, JY;Liou, JP;Shukla, P;Chang, CW;Chang, CY;Kuo, CC;Yeh, TK;Lin, CY;Wu, JS;Wu, SY;Liao, CC;Hsieh, HP
臺北醫學大學	2011	Synthesis and Biological Evaluation of 1-(4’-Indolyl and 6’-Quinolinyl)indoles as a New Class of Potent Anticancer Agents	Lia, MJ;Chang, JY;Lee, HY;Kuo, CC;Lin, MH;Hsieh, HP;Chang, CY;Wu, JS;Wu, SY;Shey, KS;Liou, JP
臺北醫學大學	2011	Synthesis and biological evaluation of 1-(40-Indolyl and 60-Quinolinyl) indoles as a new class of potent anticancer agents.	Lai, MJ;Chang, JY;Lee, HY;Kuo, CC;Lin, MH;Hsieh, HP;Chang, CY;Wu, JS;Wu, SY;Shey;KS;Liou, JP
國家衛生研究院	2010-12	Discovery of non-glycoside sodium-dependent glucose Co-transporter 2 (SGLT2) inhibitors by ligand-based virtual screening	Wu, JS;Peng, YH;Wu, JM;Hsieh, CJ;Wu, SH;Coumar, MS;Song, JS;Lee, JC;Tsai, CH;Chen, CT;Liu, YW;Chao, YS;Wu, SY
國家衛生研究院	2010-10-06	吡咯烷化合物	Jiaang, WT;Chen, X;Wu, SY;Hsieh, HP;Chao, YS
國家衛生研究院	2010-10	Structural basis for the improved potency of peroxisome proliferator-activated receptor (PPAR) agonists	Peng, YH;Coumar, MS;Leou, JS;Wu, JS;Shiao, HY;Lin, CH;Lin, WH;Lien, TW;Chen, X;Hsu, JT;Chao, YS;Huang, CF;Lyu, PC;Hsieh, HP;Wu, SY
國家衛生研究院	2010-09	Endogenous latent membrane protein 1 in Epstein-Barr virus-infected nasopharyngeal carcinoma cells attracts T lymphocytes through upregulation of multiple chemokines	Lai, HC;Hsiao, JR;Chen, CW;Wu, SY;Lee, CH;Su, IJ;Takada, K;Chang, Y
國家衛生研究院	2010-09	Cancer cells acquire mitotic drug resistance properties through beta i-tubulin mutations and alterations in the expression of beta-tubulin isotypes	Cheung, CHA;Wu, SY;Lee, TR;Chang, CY;Wu, JS;Hsieh, HP;Chang, JY
美和科技大學	2010-09	Increasing hybridoma viability and antibody repertoire after the cell fusion by the use of human plasma as an alternative supplement	Lee RJ;Wu JS;Juang RH;Wu YJ;Lin CY;Wu SY;Huang PR;Chu CH;Chin LT;Chen HM
國家衛生研究院	2010-08	Lead optimization of furanopyrimidine Aurora kinase inhibitors: Development of in vivo active agents in tumor xenograft models	Hsieh, HP;Chu, CY;Coumar, MS;Lin, WH;Chen, CT;Hsu, TA;Wu, SY;Chao, YS
國家衛生研究院	2010-06-15	Fast-forwarding hit to lead: Aurora and epidermal growth factor receptor kinase inhibitor lead identification	Coumar, MS;Chu, CY;Lin, CW;Shiao, HY;Ho, YL;Reddy, R;Lin, WH;Chen, CH;Peng, YH;Leou, JS;Lien, TW;Huang, CT;Fang, MY;Wu, SH;Wu, JS;Chittimalla, SK;Song, JS;Hsu, JT;Wu, SY;Liao, CC;Chao, YS;Hsieh, HP
國家衛生研究院	2010-03-30	Pyrrolidine compounds	Jiaang, WT;Chen, X;Wu, SY;Chao, YS;Hsieh, HP
國家衛生研究院	2010-03-11	5-Amino-2-Aroylquinolines as Highly Potent Tubulin Polymerization Inhibitors	Nien, CY;Chen, YC;Kuo, CC;Hsieh, HP;Chang, CY;Wu, JS;Wu, SY;Liou, JP;Chang, JY
國家衛生研究院	2010-02-01	Identification, SAR studies, and X-ray Co-crystallographic analysis of a novel furanopyrimidine aurora kinase a inhibitor	Coumar, MS;Tsai, MT;Chu, CY;Uang, BJ;Lin, WH;Chang, CY;Chang, TY;Leou, JS;Teng, CH;Wu, JS;Fang, MY;Chen, CH;Hsu, JTA;Wu, SY;Chao, YS;Hsieh, HP
國立聯合大學	2010	Optimizing coagulant demand by Nephelometric Turbidimeter Monitoring System (NTMS)	Cheng, WP; Yu, RF; Hsieh, YJ; Wu, SY; Huang, YW; Chen, SM
臺北醫學大學	2010	5-Amino-2-Aroylquinolines as Highly Potent Tubulin Polymerization Inhibitors	Nien, CY;Chen, YC;Kuo, CC;Hsieh, HP;Chang, CY;Wu, JS;Wu, SY;Liou, JP;Chang, JY
國家衛生研究院	2009-10	(1,3-Diphenyl-1H-pyrazol-4-yl)-methylamine analogues as inhibitors of dipeptidyl peptidases	Hsu, T;Chen, CT;Tsai, TY;Cheng, JH;Wu, SY;Chang, CN;Chien, CH;Yeh, KC;Huang, YW;Huang, CL;Huang, CY;Wu, SH;Chiang, YK;Wang, MH;Chao, YS;Chen, X;Jiaang, WT
國家衛生研究院	2009-08-13	Synthesis and evaluation of 3-aroylindoles as anticancer agents: Metabolite approach	Wu, YS;Coumar, MS;Chang, JY;Sun, HY;Kuo, FM;Kuo, CC;Chen, YJ;Chang, CY;Hsiao, CL;Liou, JP;Chen, CP;Yao, HT;Chiang, YK;Tan, UK;Chen, CT;Chu, CY;Wu, SY;Yeh, TK;Lin, CY;Hsieh, HP
中國醫藥大學	2009-08	Synthesis and Evaluation of 3-Aroylindoles as Anticancer Agents: Metabolite Approach.	(Wu YS); (Coumar MS); (Chang JY); (Sun HY); (Kuo FM); (Kuo CC); (Chen YJ); (Chang CY); (Hsiao CL); (Liou JP); (Chen CP); 姚賢宗(Hsien-Tsung Yao); (Chiang YK); (Tan UK); (Chen CT); (Chu CY); (Wu SY); (Yeh TK); (Lin CY); (Hsieh HP)*
國家衛生研究院	2009-07-23	Generation of ligand-based pharmacophore model and virtual screening for identification of novel tubulin inhibitors with potent anticancer activity	Chiang, YK;Kuo, CC;Wu, YS;Chen, CT;Coumar, MS;Wu, JS;Hsieh, HP;Chang, CY;Jseng, HY;Wu, MH;Leou, JS;Song, JS;Chang, JY;Lyu, PC;Chao, YS;Wu, SY
國家衛生研究院	2009-06	A three-dimensional pharmacophore model for dipeptidyl peptidase IV inhibitiors [Erratum: European Journal of Medicinal Chemistry. 2008 Aug;43(8):1603-1611.]	Lu, IL;Tsai, KC;Chiang, YK;Jiaang, WT;Wu, SH;Mahindroo, N;Chien, CH;Lee, SJ;Chen, X;Chao, YS;Wu, SY
國家衛生研究院	2009-05-15	Endoplasmic reticulum stress triggers XBP-1-mediated up-regulation of an EBV oncoprotein in nasopharyngeal carcinoma	Hsiao, JR;Chang, KC;Chen, CW;Wu, SY;Su, IJ;Hsu, MC;Jin, YT;Tsai, ST;Takada, K;Chang, Y
國家衛生研究院	2009-04-23	Design and structural analysis of novel pharmacophores for potent and selective peroxisome proliferator-activated receptor gamma agonists	Lin, CH;Peng, YH;Coumar, MS;Chittimalla, SK;Liao, CC;Lyn, PC;Huang, CC;Lien, TW;Lin, WH;Hsu, JT;Cheng, JH;Chen, X;Wu, JS;Chao, YS;Lee, HJ;Juo, CG;Wu, SY;Hsieh, HP
國家衛生研究院	2009-03	Discovery and development of novel furano-pyrimidine analogs as Aurora kinase inhibitors	Hsieh, HP;Coumar, MS;Lin, CW;Reddy, GR;Tsai, MT;Lin, WH;Hsu, TA;Wu, SY
國家衛生研究院	2009-02-26	Structure-based drug design of novel aurora kinase a inhibitors: Structural basis for potency and specificity	Coumar, MS;Leou, JS;Shukla, P;Wu, JS;Dixit, AK;Lin, WH;Chang, CY;Lien, TW;Tan, UK;Chen, CH;Hsu, JTA;Chao, YS;Wu, SY;Hsieh, HP
國家衛生研究院	2009-01-22	Pyrrolidine compounds	Chao, YS;Chen, X;Hsieh, HP;Jiaang, WT;Wu, SY
國立臺灣大學	2009-01	Effect of benazepril on systemic blood pressure in small breed dogs with chronic degenerative valvular diseases.	Wu, SY; Huang, HP
國家衛生研究院	2008-12-25	Synthesis and structure-activity relationships of 2-amino-1-aroylnaphthalene and 2-hydroxy-1-aroylnaphthalenes as potent antitubulin agents	Reddy, GR;Kuo, CC;Tan, UK;Coumar, MS;Chang, CY;Chiang, YK;Lai, MJ;Yeh, JY;Wu, SY;Chang, JY;Liou, JP;Hsieh, HP
國立臺灣大學	2008-11	YC-1 induces apoptosis of human renal carcinoma A498 cells in vitro and in vivo through activation of the JNK pathway.	Wu, SY; Pan, SL; Chen, TH; Liao, CH; Huang, DY; Guh, JH; Chang, YL; Kuo, SC; Lee, FY; Teng, CM.
國家衛生研究院	2008-08	A three-dimensional pharmacophore model for dipeptidyl peptidase IV inhibitors	Lu, IL;Tsai, KC;Chiang, YK;Jiaang, WT;Wu, SH;Mahindroo, N;Chien, CH;Lee, SJ;Chen, X;Chao, YS;Wu, SY
國家衛生研究院	2008-07-21	吡咯啉啶化合物	Jiaang, WT;Wu, SY;Chen, X;Chao, YS;Hsieh, HP
國家衛生研究院	2008-07-01	Pyrrolidine compounds	Jiaang, WT;Chen, X;Wu, SY;Hsieh, HP;Chao, YS

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