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Institution Date Title Author
國家衛生研究院 2019-08-20 MAP4K3/GLK promotes lung cancer metastasis by phosphorylating and activating IQGAP1 Chuang, HC;Chang, CC;Teng, CF;Hsueh, CH;Chiu, LL;Hsu, PM;Lee, MC;Hsu, CP;Chen, YR;Liu, YC;Lyu, PC;Tan, TH
國家衛生研究院 2019-07-18 AhR-ROR-gammat complex is a therapeutic target for MAP4K3/GLK(high)IL-17A(high) subpopulation of systemic lupus erythematosus Chuang, HC;Chen, YM;Chen, MH;Hung, WT;Yang, HY;Tseng, YH;Tan, TH
國家衛生研究院 2019-05-30 Regulation of Dual-Specificity Phosphatase (DUSP) ubiquitination and protein stability Chen, HF;Chuang, HC;Tan, TH
國家衛生研究院 2019-05 MAP4K3/GLK-induced AhR-RORyt complex is a novel therapeutic target for GLIC(high)IL-17A(high) subpopulation of SLE patients Chuang, HC;Tan, TH
國家衛生研究院 2019-05 Control of mucosal barrier functions and gut microbiome homeostasis by DUSP6 in colitis Kao, CY;Chang, CS;Liao, YC;Huang, CT;Ruan, JW;Lin, CM;Tan, TH;Liao, YC
國家衛生研究院 2019-05 T-cell signaling in Th17-mediated inflammation Tan, TH;Chuang, HC
國家衛生研究院 2019-03-01 MAP4K4 inhibition promotes survival of human stem cell-derived cardiomyocytes and reduces infarct size in vivo Fiedler, LR;Chapman, K;Xie, M;Maifoshie, E;Jenkins, M;Golforoush, PA;Bellahcene, M;Noseda, M;Faust, D;Jarvis, A;Newton, G;Paiva, MA;Harada, M;Stuckey, DJ;Song, W;Habib, J;Narasimham, P;Aqil, R;Sanmugalingam, D;Yan, R;Pavanello, L;Sano, M;Wang, SC;Sampson, RD;Kanayaganam, S;Taffet, GE;Michael, LH;Entman, ML;Tan, TH;Harding, SE;Low, CMR;Tralau-Stewart, C;Perrior, T;Schneider, MD
國家衛生研究院 2018-2018 MAP4K3 (GLK) Chuang, HC;Tan, TH
國家衛生研究院 2018-12 RBM4-SRSF3-MAP4K4 splicing cascade modulates the metastatic signature of colorectal cancer cell Lin, JC;Lee, YC;Tan, TH;Liang, YC;Chuang, HC;Fann, YC;Johnson, KR;Lin, YJ
國家衛生研究院 2018-09-20 PP4 deficiency leads to DNA replication stress that impairs immunoglobulin class switch efficiency Chen, MY;Hsu, WC;Hsu, SC;Yang, YS;Chuang, TH;Lin, WJ;Tan, TH;Su, YW
國家衛生研究院 2018-09-12 GLK-IKKbeta signaling induces dimerization and translocation of the AhR-RORgammat complex in IL-17A induction and autoimmune disease Chuang, HC;Tsai, CY;Hsueh, CH;Tan, TH
國家衛生研究院 2018-09-06 RBM4A-SRSF3-MAP4K4 splicing cascade constitutes a molecular mechanism for regulating brown adipogenesis Peng, HY;Liang, YC;Tan, TH;Chuang, HC;Lin, YJ;Lin, JC
國家衛生研究院 2018-08-21 DUSP6 mediates T cell receptor-engaged glycolysis and restrains TFH cell differentiation Hsu, WC;Chen, MY;Hsu, SC;Huang, LR;Kao, CY;Cheng, WH;Pan, CH;Wu, MS;Yu, GY;Hung, MS;Leu, CM;Tan, TH;Su, YW
國家衛生研究院 2018-06-19 Induction of DUSP14 ubiquitination by PRMT5-mediated arginine methylation Yang, CY;Chiu, LL;Chang, CC;Chuang, HC;Tan, TH
國家衛生研究院 2017-11 Deficiency in VHR/DUSP3, a suppressor of focal adhesion kinase, reveals its role in regulating cell adhesion and migration Chen, YR;Chou, HC;Yang, CH;Chen, HY;Liu, YW;Lin, TY;Yeh, CL;Chao, WT;Tsou, HH;Chuang, HC;Tan, TH
國家衛生研究院 2017-07-19 MAP4k3 as a biomarker and therapetic target for autoimmune disease, cancer, inflammation and il-17- associated disease Tan, TH;Chuang, HC
國家衛生研究院 2017-02 Dual-specificity phosphatase 6 deficiency regulates gut microbiome and transcriptome response against diet-induced obesity in mice Ruan, JW;Statt, S;Huang, CT;Tsai, YT;Kuo, CC;Chan, HL;Liao, YC;Tan, TH;Kao, CY
國家衛生研究院 2017-01-07 MAP4K4 and IL-6+ Th17 cells play important roles in non-obese type 2 diabetes Chuang, HC;Tan, TH
國家衛生研究院 2016-08 Downregulation of the phosphatase JKAP/DUSP22 in T Cells as a potential new biomarker of systemic lupus erythematosus nephritis Chuang, HC;Chen, YM;Hung, WT;Li, JP;Chen, DY;Lan, JL;Tan, TH
國家衛生研究院 2016-08 Roles of innate immune regulator TAPE in RIG-I signaling and antiviral defenses Chen, KR;Yang, CY;Lin, CY;Lin, WY;Lo, YC;Chuang, HC;Tan, TH;Ling, P
國家衛生研究院 2016-08 Emerging roles of an innate immune regulator TAPE in Toll-like receptors, RIG-I-like receptors, and beyond Ling, P;Chen, KR;Kao, CC;Chuang, HC;Tan, TH
國家衛生研究院 2016-08 Serine/threonine phosphatase PP4 is required for class switch recombination through recruitment of gammaH2AX Chen, MY;Chen, YP;Tan, TH;Su, YW
國家衛生研究院 2016-08 Molecular mechanisms of DUSP22 ablation in enhancing EGFR-mediated lung tumor development: Potential involvement of immunosuppression Lin, HP;Ho, HM;Chang, CW;Tan, TH;Lin, WJ
國家衛生研究院 2016-08 HGK/MAP4K4 deficiency induces TRAF2 stabilization and Th17 differentiation leading to T-cell-mediated type 2 diabetes Chuang, HC;Tan, TH
國家衛生研究院 2016-07 GLK/MAP4K3 overexpression associates with recurrence risk for non-small cell lung cancer Hsu, CP;Chuang, HC;Lee, MC;Tsou, HH;Lee, LW;Li, JP;Tan, TH
國家衛生研究院 2016-07 Prediction of early hepatocellular carcinoma recurrence using germinal center kinase-like kinase Ho, CH;Chuang, HC;Wu, IC;Tsai, HW;Lin, YJ;Sun, HY;Young, KC;Chiu, YC;Cheng, PN;Liu, WC;Tan, TH;Chang, TT
國家衛生研究院 2016-05 A multi-prong global study provides insights to gut microbiota and mucosal immunity in dusp6-deficiency conferred obesity-resistance Ruan, JW;Statt, S;Huang, CT;Tsai, YT;Chan, HL;Tan, TH;Kao, CY
國家衛生研究院 2016-05 Roles of innate immune regulator TAPE in RIG-I signaling and antiviral defenses Chen, KR;Yang, CY;Lin, CY;Lin, WY;Lo, YC;Chuang, HC;Tan, TH;Ling, P
國家衛生研究院 2016-05 Emerging roles of an innate immune regulator TAPE in Toll-like receptors, RIG-I-like receptors, and beyond Ling, P;Cheni, KR;Kao, CC;Chuang, HC;Tan, TH
國家衛生研究院 2016-03-08 Epigenetic regulation of HGK/MAP4K4 in T cells of type 2 diabetes patients Chuang, HC;Wang, JS;Lee, IT;Sheu, WH;Tan, TH
國家衛生研究院 2016-01 MAP4K family kinases in immunity and inflammation Chuang, HC;Wang, X;Tan, TH
國家衛生研究院 2016-01 TRAF2-mediated Lys63-linked ubiquitination of DUSP14/MKP6 is essential for its phosphatase activity Yang, CY;Chiu, LL;Tan, TH
國立交通大學 2014-12-08T15:49:04Z A hybrid strategy for Gilbert's channel characterization using gradient and annealing techniques Tan, TH; Chang, WW
國立交通大學 2014-12-08T15:48:56Z Fuzzy neural systems for controlling sound localisation in stereophonic reproduction Chang, PR; Tan, TH
國立交通大學 2014-12-08T15:43:40Z Robust vector quantization for wireless channels Chang, WW; Tan, TH; Wang, DY
國立交通大學 2014-12-08T15:27:39Z Estimation of Gilbert's model parameters using the simulated annealing method Tan, TH; Chang, WW
國立交通大學 2014-12-08T15:27:37Z Statistical characterization of error sequences and its applications to error control Chang, WW; Tan, TH
國立交通大學 2014-12-08T15:02:30Z Estimation of the Gilbert model parameters using the simulated annealing method Tan, TH; Chang, WW
國家衛生研究院 2014-09-30 Map kinase kinase kinase kinase 3 (MAP4K3) as a biomarker and therapeutic target for autoimmune disease, cancer, inflammation and IL-17-associated disease Tan, TH;Chuang, HC
國家衛生研究院 2014-09-12 PP4 is essential for germinal center formation and class switch recombination in mice Chen, MY;Chen, YP;Wu, MS;Yu, GY;Lin, WJ;Tan, TH;Su, YW
國家衛生研究院 2014-08-06 HGK/MAP4K4 deficiency induces TRAF2 stabilization and Th17 differentiation leading to insulin resistance Chuang, HC;Sheu, WH;Lin, YT;Tsai, CY;Yang, CY;Cheng, YJ;Huang, PY;Li, JP;Chiu, LL;Wang, X;Xie, M;Schneider, MD;Tan, TH
國家衛生研究院 2014-05-07 Protein phosphatase 4 is an essential positive regulator for Treg development, function, and protective gut immunity Liao, FH;Shui, JW;Hsing, EW;Hsiao, WY;Lin, YC;Chan, YC;Tan, TH;Huang, CY
國家衛生研究院 2014-04-09 The phosphatase JKAP/DUSP22 inhibits T-cell receptor signalling and autoimmunity by inactivating Lck Li, JP;Yang, CY;Chuang, HC;Lan, JL;Chen, DY;Chen, YM;Wang, X;Chen, AJ;Belmont, JW;Tan, TH
國家衛生研究院 2014-02-15 Dual-specificity Phosphatase 14 (DUSP14/MKP6) negatively regulates TCR signaling by inhibiting TAB1 activation Yang, CY;Li, JP;Chiu, LL;Lan, JL;Chen, DY;Chuang, HC;Huang, CY;Tan, TH
國家衛生研究院 2014-02 The CUL7/F-box and WD repeat domain containing 8 (CUL7/Fbxw8) ubiquitin ligase promotes degradation of hematopoietic progenitor kinase 1 Wang, H;Chen, Y;Lin, P;Li, L;Zhou, G;Liu, G;Logsdon, C;Jin, J;Abbruzzese, JL;Tan, TH;Wang, H
國家衛生研究院 2013-10 Germinal center kinase-like kinase overexpression in T cells as a novel biomarker in rheumatoid arthritis Chen, YM;Chuang, HC;Lin, WC;Tsai, CY;Wu, CW;Gong, NR;Hung, WT;Lan, TH;Lan, JL;Tan, TH;Chen, DY
國家衛生研究院 2013-07 The serine/threonine phosphatase PP4 is required for pro-B cell development through its promotion of immunoglobulin VDJ recombination Su, YW;Chen, YP;Chen, MY;Reth, M;Tan, TH
國家衛生研究院 2012-10-05 Attenuation of T cell receptor signaling by serine phosphorylation-mediated lysine 30 ubiquitination of SLP-76 protein Wang, X;Li, JP;Chiu, LL;Lan, JL;Chen, DY;Boomer, J;Tan, TH
國家衛生研究院 2012-09-14 TBK1-associated protein in endolysosomes (TAPE)/CC2D1A is a key regulator linking RIG-I-like receptors to antiviral immunity Chen, KR;Chang, CH;Huang, CY;Lin, CY;Lin, WY;Lo, YC;Yang, CY;Hsing, EW;Chen, LF;Shih, SR;Shiau, AL;Lei, HY;Tan, TH;Ling, P
國家衛生研究院 2012-08-06 Germinal center kinase-like kinase (GLK/MAP4K3) expression is increased in adult-onset Still's disease and may act as an activity marker Chen, DY;Chuang, HC;Lan, JL;Chen, YM;Hung, WT;Lai, KL;Tan, TH

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