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机构 日期 题名 作者
國家衛生研究院 2019-08-20 MAP4K3/GLK promotes lung cancer metastasis by phosphorylating and activating IQGAP1 Chuang, HC;Chang, CC;Teng, CF;Hsueh, CH;Chiu, LL;Hsu, PM;Lee, MC;Hsu, CP;Chen, YR;Liu, YC;Lyu, PC;Tan, TH
國家衛生研究院 2019-07-18 AhR-ROR-gammat complex is a therapeutic target for MAP4K3/GLK(high)IL-17A(high) subpopulation of systemic lupus erythematosus Chuang, HC;Chen, YM;Chen, MH;Hung, WT;Yang, HY;Tseng, YH;Tan, TH
國家衛生研究院 2019-05-30 Regulation of Dual-Specificity Phosphatase (DUSP) ubiquitination and protein stability Chen, HF;Chuang, HC;Tan, TH
國家衛生研究院 2019-05 MAP4K3/GLK-induced AhR-RORyt complex is a novel therapeutic target for GLIC(high)IL-17A(high) subpopulation of SLE patients Chuang, HC;Tan, TH
國家衛生研究院 2019-05 Control of mucosal barrier functions and gut microbiome homeostasis by DUSP6 in colitis Kao, CY;Chang, CS;Liao, YC;Huang, CT;Ruan, JW;Lin, CM;Tan, TH;Liao, YC
國家衛生研究院 2019-05 T-cell signaling in Th17-mediated inflammation Tan, TH;Chuang, HC
國家衛生研究院 2019-03-01 MAP4K4 inhibition promotes survival of human stem cell-derived cardiomyocytes and reduces infarct size in vivo Fiedler, LR;Chapman, K;Xie, M;Maifoshie, E;Jenkins, M;Golforoush, PA;Bellahcene, M;Noseda, M;Faust, D;Jarvis, A;Newton, G;Paiva, MA;Harada, M;Stuckey, DJ;Song, W;Habib, J;Narasimham, P;Aqil, R;Sanmugalingam, D;Yan, R;Pavanello, L;Sano, M;Wang, SC;Sampson, RD;Kanayaganam, S;Taffet, GE;Michael, LH;Entman, ML;Tan, TH;Harding, SE;Low, CMR;Tralau-Stewart, C;Perrior, T;Schneider, MD
國家衛生研究院 2018-2018 MAP4K3 (GLK) Chuang, HC;Tan, TH
國家衛生研究院 2018-12 RBM4-SRSF3-MAP4K4 splicing cascade modulates the metastatic signature of colorectal cancer cell Lin, JC;Lee, YC;Tan, TH;Liang, YC;Chuang, HC;Fann, YC;Johnson, KR;Lin, YJ
國家衛生研究院 2018-09-20 PP4 deficiency leads to DNA replication stress that impairs immunoglobulin class switch efficiency Chen, MY;Hsu, WC;Hsu, SC;Yang, YS;Chuang, TH;Lin, WJ;Tan, TH;Su, YW
國家衛生研究院 2018-09-12 GLK-IKKbeta signaling induces dimerization and translocation of the AhR-RORgammat complex in IL-17A induction and autoimmune disease Chuang, HC;Tsai, CY;Hsueh, CH;Tan, TH
國家衛生研究院 2018-09-06 RBM4A-SRSF3-MAP4K4 splicing cascade constitutes a molecular mechanism for regulating brown adipogenesis Peng, HY;Liang, YC;Tan, TH;Chuang, HC;Lin, YJ;Lin, JC
國家衛生研究院 2018-08-21 DUSP6 mediates T cell receptor-engaged glycolysis and restrains TFH cell differentiation Hsu, WC;Chen, MY;Hsu, SC;Huang, LR;Kao, CY;Cheng, WH;Pan, CH;Wu, MS;Yu, GY;Hung, MS;Leu, CM;Tan, TH;Su, YW
國家衛生研究院 2018-06-19 Induction of DUSP14 ubiquitination by PRMT5-mediated arginine methylation Yang, CY;Chiu, LL;Chang, CC;Chuang, HC;Tan, TH
國家衛生研究院 2017-11 Deficiency in VHR/DUSP3, a suppressor of focal adhesion kinase, reveals its role in regulating cell adhesion and migration Chen, YR;Chou, HC;Yang, CH;Chen, HY;Liu, YW;Lin, TY;Yeh, CL;Chao, WT;Tsou, HH;Chuang, HC;Tan, TH
國家衛生研究院 2017-07-19 MAP4k3 as a biomarker and therapetic target for autoimmune disease, cancer, inflammation and il-17- associated disease Tan, TH;Chuang, HC
國家衛生研究院 2017-02 Dual-specificity phosphatase 6 deficiency regulates gut microbiome and transcriptome response against diet-induced obesity in mice Ruan, JW;Statt, S;Huang, CT;Tsai, YT;Kuo, CC;Chan, HL;Liao, YC;Tan, TH;Kao, CY
國家衛生研究院 2017-01-07 MAP4K4 and IL-6+ Th17 cells play important roles in non-obese type 2 diabetes Chuang, HC;Tan, TH
國家衛生研究院 2016-08 Downregulation of the phosphatase JKAP/DUSP22 in T Cells as a potential new biomarker of systemic lupus erythematosus nephritis Chuang, HC;Chen, YM;Hung, WT;Li, JP;Chen, DY;Lan, JL;Tan, TH
國家衛生研究院 2016-08 Roles of innate immune regulator TAPE in RIG-I signaling and antiviral defenses Chen, KR;Yang, CY;Lin, CY;Lin, WY;Lo, YC;Chuang, HC;Tan, TH;Ling, P
國家衛生研究院 2016-08 Emerging roles of an innate immune regulator TAPE in Toll-like receptors, RIG-I-like receptors, and beyond Ling, P;Chen, KR;Kao, CC;Chuang, HC;Tan, TH
國家衛生研究院 2016-08 Serine/threonine phosphatase PP4 is required for class switch recombination through recruitment of gammaH2AX Chen, MY;Chen, YP;Tan, TH;Su, YW
國家衛生研究院 2016-08 Molecular mechanisms of DUSP22 ablation in enhancing EGFR-mediated lung tumor development: Potential involvement of immunosuppression Lin, HP;Ho, HM;Chang, CW;Tan, TH;Lin, WJ
國家衛生研究院 2016-08 HGK/MAP4K4 deficiency induces TRAF2 stabilization and Th17 differentiation leading to T-cell-mediated type 2 diabetes Chuang, HC;Tan, TH
國家衛生研究院 2016-07 GLK/MAP4K3 overexpression associates with recurrence risk for non-small cell lung cancer Hsu, CP;Chuang, HC;Lee, MC;Tsou, HH;Lee, LW;Li, JP;Tan, TH

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