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教育部委託研究計畫      計畫執行:國立臺灣大學圖書館
 
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機構 日期 題名 作者
國家衛生研究院 2021-06-29 Design and synthesis of novel orally selective and type II pan-TRK inhibitors to overcome mutations by property-driven optimization Li, MC;Lin, WH;Wang, PC;Su, YC;Chen, PY;Fan, CM;Chen, CP;Huang, CL;Chiu, CH;Chang, L;Chen, CT;Yeh, TK;Hsieh, HP
國家衛生研究院 2021-04-16 Development of a robust scale-up synthetic route for BPR1K871: A clinical candidate for the treatment of acute myeloid leukemia and solid tumors Reddy, JS;Chen, CM;Coumar, MS;Sun, HY;Sun, N;Hsieh, HP
國家衛生研究院 2021-04-13 Chlorinated briarane diterpenoids from octocoral Briareum stechei (Kükenthal, 1908) Huynh, TH;Lee, GH;Tanaka, J;Hsieh, HP;Kelvin Tsou, L;Zhang, MM;Kuo, TJ;Wen, ZH;Lu, CK;Sung, PJ
國家衛生研究院 2021-02-22 Mimicking H3 substrate arginine in the design of G9a lysine methyltransferase inhibitors for cancer therapy: A computational study for structure-based drug design Chandar Charles, MR;Li, MC;Hsieh, HP;Coumar, MS
國家衛生研究院 2021-01-31 Briarenols W-Z: Chlorine-containing polyoxygenated briaranes from octocoral briareum stechei (Kükenthal, 1908) Chen, YY;Zhang, YL;Lee, GH;Tsou, LK;Zhang, MM;Hsieh, HP;Chen, JJ;Ko, CY;Wen, ZH;Sung, PJ
國家衛生研究院 2021-01-15 One-pot synthesis of dibenzo[b,f]oxepines and total synthesis of bauhinoxepin C Taweesak, P;Thongaram, P;Kraikruan, P;Thanetchaiyakup, A;Chuanopparat, N;Hsieh, HP;Uang, BJ;Ngernmeesri, P
中山醫學大學 2021 Chlorinated briarane diterpenoids from octocoral Briareum stechei (Kukenthal, 1908) Huynh, TH; Lee, GH; Tanaka, J; Hsieh, HP; Tsou, LK; Zhang, MZM; Kuo, TJ; Wen, ZH; Lu, CK; Sung, PJ
國家衛生研究院 2020-12-10 Tumor-agnostic inhibitors in oncology: A new phase for precision medicine Li, MC;Hsieh, HP
國家衛生研究院 2020-07-07 Overcoming vincristine resistance in cancer: Computational design and discovery of piperine-inspired P-glycoprotein inhibitors Syed, SB;Lin, SY;Arya, H;Fu, IH;Yeh, TK;Charles, MRC;Periyasamy, L;Hsieh, HP;Coumar, MS
國家衛生研究院 2020-05 Drug-like property optimization: Discovery of orally bioavailable quinazoline-based multi-targeted kinase inhibitors Lin, SY;Chang, CF;Coumar, MS;Chen, PY;Kuo, FM;Chen, CH;Li, MC;Lin, WH;Kuo, PC;Wang, SY;Li, AS;Lin, CY;Yang, CM;Yeh, TK;Song, JS;Hsu, JTA;Hsieh, HP
國家衛生研究院 2020-03-01 A selective Aurora-A 5'-UTR siRNA inhibits tumor growth and metastasis Lai, CH;Chen, RY;Hsieh, HP;Tsai, SJ;Chang, KC;Yen, CJ;Huang, YC;Liu, YW;Lee, JC;Lai, YC;Hung, LY;Lin, BW
國家衛生研究院 2020-01 Identification of novel quinoline inhibitor for EHMT2/G9a through virtual screening Chandar Charles, MR;Mahesh, A;Lin, SY;Hsieh, HP;Dhayalan, A;Coumar, MS
國家衛生研究院 2019-10-08 Identification of two novel small compounds that inhibit liver cancer formation in zebrafish and analysis of their conjugation to nanodiamonds to further reduce toxicity Tseng, PH;Sie, ZL;Liu, MC;Lin, HS;Yang, WY;Lin, TY;Hsieh, HP;Hung, SC;Cheng, CL;Wang, HD;Chang, HH;Yuh, CH
國家衛生研究院 2019-10 The molecular mechanisms of EpCAM in regulating tumor progression and development of anti-EpCAM antibodies for colon cancer diagnosis and therapy Wu, HC;Liang, KH;Hsieh, HP;Li, WS
國家衛生研究院 2019-10 Discovery of clinical candidate DBPR112, a furanopyrimidine-based epidermal growth factor receptor inhibitor for the treatment of non-small cell lung cancer Hsieh, HP;Chang, JY;Yeh, CT;Lin, SY;Ke, YY;Lin, WH;Hsu, TA;Wu, SY;Yeh, TK
國家衛生研究院 2019-09-28 Design of drug-like hepsin inhibitors against prostate cancer and kidney stones Blay, V;Li, MC;Ho, SP;Stoller, ML;Hsieh, HP;Houston, DR
國家衛生研究院 2019-09-27 Discovery of a furanopyrimidine-based epidermal growth factor receptor inhibitor (DBPR112) as a clinical candidate for the treatment of non-small cell lung cancer Lin, SY;Chang Hsu, Y;Peng, YH;Ke, YY;Lin, WH;Sun, HY;Shiao, HY;Kuo, FM;Chen, PY;Lien, TW;Chen, CH;Chu, CY;Wang, SY;Yeh, KC;Chen, CP;Hsu, TA;Wu, SY;Yeh, TK;Chen, CT;Hsieh, HP
國家衛生研究院 2019-09 Design of a potent anticancer lead inspired by natural products from traditional Indian medicine Arya, H;Yadav, CS;Lin, SY;Syed, SB;Charles, MRC;Kannadasan, S;Hsieh, HP;Singh, SS;Gajurel, PR;Coumar, MS
國家衛生研究院 2019-07-21 Lysosomal cysteine protease cathepsin S is involved in cancer cell motility by regulating store-operated Ca(2+) entry Lin, HH;Chen, SJ;Shen, MR;Huang, YT;Hsieh, HP;Lin, SY;Lin, CC;Chang, WW;Chang, JY
國家衛生研究院 2019-07 Dual Kit/Aur inhibitors as chemosensitizing agents for the treatment of melanoma: Design, synthesis, docking studies and functional investigation Quattrini, L;Coviello, V;Sartini, S;Di Desidero, T;Orlandi, P;Ke, YY;Liu, KL;Hsieh, HP;Bocci, G;La Motta, C
國家衛生研究院 2019-05-29 Insights for the design of protein lysine methyltransferase G9a inhibitors Charles, MRC;Dhayalan, A;Hsieh, HP;Coumar, MS
國家衛生研究院 2018-11 Biomimetic Syntheses of (±)‐Isopalhinine A, (±)‐Palhinine A, and (±)‐Palhinine D Chen, CM;Shiao, HY;Uang, BJ;Hsieh, HP
國家衛生研究院 2018-07-26 Delineating the active site architecture of G9a lysine methyltransferase through substrate and inhibitor binding mode analysis: A molecular dynamics study M, RCC;Hsieh, HP;Coumar, MS
國家衛生研究院 2018-07 Clinical candidate DBPR112: A novel epidermal growth factor receptor inhibitor as a promising treatment for non-small cell lung cancer Hsieh, HP;Chang, JY;Kuo, CC;Hsu, J
國家衛生研究院 2018-07 Blockage of EGFR signaling repurposes tumor metabolism through suppression of glycolysis and Kreb cycle in head and neck cancer Kuo, CC;Chang, JY;Hsieh, HP;Kung, HJ;Chang, HH;Huang, CH;Kuo, CC;Ke, YY

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